Effect of Mild Cognitive Impairment on Activities of Daily Living in Hospitalized Patients with Sub-acute Heart Failure

• Published in: Physical Therapy Japan Vol. 48; no. 4; pp. 362 - 369
• Main Authors: MATSUKAWA, Yuko, MATSUSHIMA, Keisuke, TAKAHASHI, Ren, YOKOTA, Junichi
• Format: Journal Article
• Language: Japanese
• Published: Japanese Physical Therapy Association 2021; 公益社団法人日本理学療法士協会
• Subjects: Activities of daily living; Heart failure; Mild cognitive impairment; Physical Therapy; 心不全; 理学療法; 軽度認知機能障害
• ISSN: 0289-3770; 2189-602X
• DOI: 10.15063/rigaku.11971

Objective: This study aimed to clarify whether the presence of mild cognitive impairment (MCI) limits the effects of sub-acute phase physical therapy (PT) on activities of daily living (ADL) improvement in patients with heart failure.Methods: This was a single-center case-control study. In total, 155 patients who performed ADL independently before hospital admission were included in the analysis. The patients were divided into an MCI and a control group. Physical function before and after PT in the hospital were compared between the groups. Additionally, multiple regression analysis was used to evaluate the associated factors of the Barthel index (BI) at hospital discharge.Results: At the commencement of PT, short physical performance battery (SPPB) and BI were significantly lower in the MCI group. At hospital discharge, the MCI group had significantly lower SPPB and 6-minute walking distance. However, there were no significant differences in BI at hospital discharge between the groups. Multivariate analysis showed that SPPB was associated with BI at hospital discharge.Conclusion: Heart failure patients with MCI had a higher risk of BI decline at admission than patients in the control group, but the effect of PT on BI improvement was found to be similar regardless of MCI status. This may allow heart failure patients with MCI to perform ADL independently again.