A case of metastatic hypopharyngeal cancer of the gallbladder

• Published in: Tando Vol. 34; no. 4; pp. 680 - 686
• Main Authors: Hatori, Takashi, Miyazaki, Masaru, Kato, Atsushi, Tomizawa, Satoshi, Imai, Shunichi, Yoshizumi, Arihito, Aida, Shinsuke, Itano, Osamu
• Format: Journal Article
• Language: Japanese
• Published: Japan Biliary Association 31.10.2020; 一般社団法人 日本胆道学会
• Subjects: gallbladder metastasis; hypopharyngeal cancer; 下咽頭癌; 胆嚢転移
• ISSN: 0914-0077; 1883-6879
• DOI: 10.11210/tando.34.680

A 68-year-old man underwent total laryngopharyngoesophagectomy for hypopharyngeal cancer. Pathological diagnosis showed poorly differentiated squamous cell carcinoma, pT3N2bM0 StageIVA. Two years after surgery, PET-CT showed abnormal uptake in the gallbladder. Contrast enhanced abdominal CT revealed consecutive tumors of 30mm in the fundus and 25mm in the neck of the gallbladder. MRI showed similar findings, thus the gallbladder cancer was suspected. Hepatectomy of segment 4a and 5 was performed. There was no lesion in the mucosa and the histology was similar to that of a previous hypopharyngeal cancer. Final pathological diagnosis was gallbladder metastasis of hypopharyngeal cancer. Gallbladder metastasis of hypopharyngeal cancer are extremely rare. Renal cell carcinoma, malignant melanoma, gastric cancer and breast cancer have been reported as the primary tumor of gallbladder metastasis. Gallbladder metastasis of hypopharyngeal cancer has not been reported so far in Japan as well as in the world.