Study Group for Establishment of Diagnosis of Hereditary Gastrointestinal Tract Cancer Syndromes Based on a Next-Generation Sequencing Technology

• Published in: JOURNAL OF FAMILIAL TUMORS Vol. 19; no. 1; pp. 15 - 18
• Main Authors: Ishida, Hideyuki, Eguchi, Hidetaka, SGHGCS, Okazaki, Yasushi
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society for Familial Tumors 2019; 一般社団法人日本遺伝性腫瘍学会; The Japanese Society for Hereditary Tumors
• Subjects: Gastrointestinal cancer syndrome, next-generation sequencer, genetic test; 消化管腫瘍症候群，次世代シーケンサー，遺伝学的検査
• ISSN: 1346-1052; 2189-6674
• DOI: 10.18976/jsft.19.1_15

Clinical features of the hereditary gastrointestinal cancer syndrome overlap each other to some extent, and thus it is sometimes difficult to provide a definite diagnosis solely based on the clinico-pathological factors and family cancer history. In order to solve this big-issue, we established a Study Group for Establishment of Diagnosis of Hereditary Gastrointestinal Tract Cancer Syndromes Based on a Next-Generation Sequencing Technology (SGHGCS) in 2013. We briefly summarize our research activities thus far in accordance with the related ones of domestic and international. In 2019, the era of cancer-genome medicine comes finally true here in Japan. Numbers of problems to be solved about this are assumed. A possible establishment of a collaborative relationship among various study groups relative to the familial cancer may provide a clue to cope with these important matters.