NIBIOHN Studies for Human Gut Health

• Published in: Chōnai saikingaku zasshi Vol. 39; no. 1; pp. 9 - 19
• Main Authors: KUNISAWA, Jun, HOSOMI, Koji
• Format: Journal Article
• Language: English; Japanese
• Published: Tokyo The Intestinal Microbiology Society 2025; Japan Science and Technology Agency
• Subjects: Bacteria; Diabetes mellitus; Digestive system; Gastrointestinal tract; gut microbiome; Intestinal microflora; Intestine; Medical innovations; Microbiomes; Microorganisms; postbiotics; precision nutrition; Research facilities; Research institutions
• ISSN: 1343-0882; 1349-8363
• DOI: 10.11209/jim.39.9

The National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) conducts large-cohort studies of the Japanese gut microbiome to understand the functions and roles of microorganisms in our health and lifestyles. Also, aiming to contribute to the development of this research field, we are working to support other research institutions by providing standardized protocols and developing analytical tools. In this regard, we promote gut microbiome research that combines human cohorts and basic experiments. For example, we found an intestinal bacterium that can prevent and/or improve obesity and diabetes and its underlying mechanisms, and have examined postbiotics produced by intestinal bacteria and their functions. We also promote precision research focusing on individual differences in the gut microbiome. Here, we introduce an overview of gut microbiome studies at NIBIOHN and our recent findings.