頭蓋内外内頸動脈の血管構造に関する検討

「はじめに」頭蓋内内頸動脈の動脈硬化性狭窄病変は海綿静脈洞部に好発することが知られている1)16). また, 内頸動脈は筋性動脈であるが10)11), 頭蓋内では頭蓋外と異なり, 外弾性板がなく弾性繊維はほとんど内弾性板に集中していることも知られている3)6)21)23). 今回, われわれは, 解剖体を用いて, 頭蓋内内頸動脈における外弾性板の消失部位を確認し, 動脈硬化性狭窄病変との関連5)14)18-20)について検討を行った....

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Published in脳卒中の外科 Vol. 35; no. 1; pp. 30 - 33
Main Authors 林, 央周, 桑山, 直也, 堀, 恵美子, 増岡, 徹, 平島, 豊, 遠藤, 俊郎
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本脳卒中の外科学会 2007
日本脳卒中の外科学会
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ISSN0914-5508
1880-4683
DOI10.2335/scs.35.30

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Abstract 「はじめに」頭蓋内内頸動脈の動脈硬化性狭窄病変は海綿静脈洞部に好発することが知られている1)16). また, 内頸動脈は筋性動脈であるが10)11), 頭蓋内では頭蓋外と異なり, 外弾性板がなく弾性繊維はほとんど内弾性板に集中していることも知られている3)6)21)23). 今回, われわれは, 解剖体を用いて, 頭蓋内内頸動脈における外弾性板の消失部位を確認し, 動脈硬化性狭窄病変との関連5)14)18-20)について検討を行った.
AbstractList 「はじめに」頭蓋内内頸動脈の動脈硬化性狭窄病変は海綿静脈洞部に好発することが知られている1)16). また, 内頸動脈は筋性動脈であるが10)11), 頭蓋内では頭蓋外と異なり, 外弾性板がなく弾性繊維はほとんど内弾性板に集中していることも知られている3)6)21)23). 今回, われわれは, 解剖体を用いて, 頭蓋内内頸動脈における外弾性板の消失部位を確認し, 動脈硬化性狭窄病変との関連5)14)18-20)について検討を行った.
Author 遠藤, 俊郎
堀, 恵美子
桑山, 直也
林, 央周
平島, 豊
増岡, 徹
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References 18) Ross R: Atherosclerosis-An inflammatory disease. N Engl J Med 340: 115-126, 1999
10) Kondo S et al: Cerebral aneurysms arising at nonbranching sites. Stroke 28: 398-404, 1997
23) 山田致知,萬年 甫:実習解剖学.南江堂,1985
19) Stary HC et al: A definition if the intima of human arteries and of its atherosclerosis-prone regions. Circulation 85: 391-405, 1992
16) Raju S, Fredericks RK: Carotid siphon stenosis. J Cardiovasc Surg 28: 671-677, 1987
2) Fang H: A comparison of blood vessels of the brain and peripheral blood vessels, in Wright IS, Millikan CH (eds) : Cerebral Vascular Diseases. New York, Grune & Stratton Inc, 1958, pp17-22
15) Qui Y, Tarbell JM: Interaction between wall shear stress and circumferential strain affects endothelial cell biochemical production. J Vasc Res 37: 147-157, 2000
24) Zarins CK, Giddens DP, Bharadvaj BK, et al: Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res 53: 502-514, 1983
9) Hori E, Hayashi N, Masuoka T, et al: Correlation of plaque localization with characteristics of the cervical carotid artery wall. Surg Cereb Stroke 33: 35-38, 2005 (Jpn
3) Fujimoto KMD: 'Medial defects' in the prenatal human cerebral arteries. Stroke 27: 706-708, 1996
4) Glagov S, Zarins C, Gieedns DP, et al: Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries. Arch Pathol Lab Med 112: 1018- 1031, 1988
17) Ratinov G: Extradural intracranial portion of carotid artery. Arch Neurol 10: 66-73, 1964
14) Mitchell GM et al: A morphological study of the long-term repair process in experimentally stretched but unruptured arteies and veins. Br J Plast Surg 49: 34-40, 1996
11) Kondo S et al: Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in rats. Stroke 29: 181-189, 1998
12) Ku DN, Giddens DP, Zarins CK, et al: Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Atherosclerosis 5: 293-302, 1985
1) Craig et al: Intracranial internal carotid stenosis. Stroke 13: 825-828, 1982
21) 戸苅近太郎:組織学,第13版.南山堂,1970, pp93-97
20) Stehbens WE: Vascular Pathology. Chapman and Hall, London, 1995
22) Wilkinson IMS: The vertebral artery. Extracranial and intracranial strucure. Arch Neurol 27: 392-396, 1972
6) 橋本信夫:クモ膜下出血―基礎から臨床まで―脳動脈瘤の発生機序.循環器学 17: 456-458, 1997
7) Hassler O: Morphological studies on the large cerebral arteries, with reference to the aetiology of subarachnoid hemorrhage. Acta Psychiatr Scand (suppl 154): 1, 1961
5) Glynn LE: Medial defects in the circle of Willis and their relation to aneurysm formation. J Pathol Bact 51: 213-222, 1940
13) Malek AM, Alper SL, Izumo S: Hemodynamic shear stress and its role in atherosclerosis. JAMA 282: 2035-2042, 1999
8) Hassler O: Physiological intima cushions in the large cerebral arteries of young individuals. Acta Pathol Microbiol Scand 55: 19, 1962
References_xml – reference: 16) Raju S, Fredericks RK: Carotid siphon stenosis. J Cardiovasc Surg 28: 671-677, 1987
– reference: 18) Ross R: Atherosclerosis-An inflammatory disease. N Engl J Med 340: 115-126, 1999
– reference: 12) Ku DN, Giddens DP, Zarins CK, et al: Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Atherosclerosis 5: 293-302, 1985
– reference: 19) Stary HC et al: A definition if the intima of human arteries and of its atherosclerosis-prone regions. Circulation 85: 391-405, 1992
– reference: 1) Craig et al: Intracranial internal carotid stenosis. Stroke 13: 825-828, 1982
– reference: 8) Hassler O: Physiological intima cushions in the large cerebral arteries of young individuals. Acta Pathol Microbiol Scand 55: 19, 1962
– reference: 23) 山田致知,萬年 甫:実習解剖学.南江堂,1985
– reference: 9) Hori E, Hayashi N, Masuoka T, et al: Correlation of plaque localization with characteristics of the cervical carotid artery wall. Surg Cereb Stroke 33: 35-38, 2005 (Jpn)
– reference: 20) Stehbens WE: Vascular Pathology. Chapman and Hall, London, 1995
– reference: 21) 戸苅近太郎:組織学,第13版.南山堂,1970, pp93-97
– reference: 15) Qui Y, Tarbell JM: Interaction between wall shear stress and circumferential strain affects endothelial cell biochemical production. J Vasc Res 37: 147-157, 2000
– reference: 2) Fang H: A comparison of blood vessels of the brain and peripheral blood vessels, in Wright IS, Millikan CH (eds) : Cerebral Vascular Diseases. New York, Grune & Stratton Inc, 1958, pp17-22
– reference: 22) Wilkinson IMS: The vertebral artery. Extracranial and intracranial strucure. Arch Neurol 27: 392-396, 1972
– reference: 3) Fujimoto KMD: 'Medial defects' in the prenatal human cerebral arteries. Stroke 27: 706-708, 1996
– reference: 24) Zarins CK, Giddens DP, Bharadvaj BK, et al: Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res 53: 502-514, 1983
– reference: 6) 橋本信夫:クモ膜下出血―基礎から臨床まで―脳動脈瘤の発生機序.循環器学 17: 456-458, 1997
– reference: 5) Glynn LE: Medial defects in the circle of Willis and their relation to aneurysm formation. J Pathol Bact 51: 213-222, 1940
– reference: 17) Ratinov G: Extradural intracranial portion of carotid artery. Arch Neurol 10: 66-73, 1964
– reference: 4) Glagov S, Zarins C, Gieedns DP, et al: Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries. Arch Pathol Lab Med 112: 1018- 1031, 1988
– reference: 11) Kondo S et al: Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in rats. Stroke 29: 181-189, 1998
– reference: 13) Malek AM, Alper SL, Izumo S: Hemodynamic shear stress and its role in atherosclerosis. JAMA 282: 2035-2042, 1999
– reference: 14) Mitchell GM et al: A morphological study of the long-term repair process in experimentally stretched but unruptured arteies and veins. Br J Plast Surg 49: 34-40, 1996
– reference: 7) Hassler O: Morphological studies on the large cerebral arteries, with reference to the aetiology of subarachnoid hemorrhage. Acta Psychiatr Scand (suppl 154): 1, 1961
– reference: 10) Kondo S et al: Cerebral aneurysms arising at nonbranching sites. Stroke 28: 398-404, 1997
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