環境保健研究のジレンマ

「1. はじめに」環境保健はヒトの健康と環境の相互作用を解明する一学術分野である. 環境中に存在する有害因子(以下, 環境有害因子)には, 化学物質の曝露だけでなく, 廃棄物汚染, 越境汚染, 地球(および生活)環境変化に伴う温暖化(暑熱, 洪水・ゲリラ豪雨, 生物媒介感染症の拡大)や紫外線照射などが含まれる. これらがヒトの健康にどのような/どのように影響を与えるが環境保健の主たる研究目的であり, 途上国では金属鉱山・採掘や農薬撒布による健康リスクに関する研究が盛んにおこなわれているが, 先進国では環境による小児への健康影響に関心が向けられている. 1970年代後半に鉛による健康影響に関する...

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Published in日本衛生学雑誌 Vol. 73; no. 2; pp. 148 - 155
Main Authors 村田, 勝敬, 岩田, 豊人, 苅田, 香苗, 前田, 恵理
Format Journal Article
LanguageJapanese
Published 一般社団法人日本衛生学会 2018
日本衛生学会
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Online AccessGet full text
ISSN0021-5082
1882-6482
DOI10.1265/jjh.73.148

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Abstract 「1. はじめに」環境保健はヒトの健康と環境の相互作用を解明する一学術分野である. 環境中に存在する有害因子(以下, 環境有害因子)には, 化学物質の曝露だけでなく, 廃棄物汚染, 越境汚染, 地球(および生活)環境変化に伴う温暖化(暑熱, 洪水・ゲリラ豪雨, 生物媒介感染症の拡大)や紫外線照射などが含まれる. これらがヒトの健康にどのような/どのように影響を与えるが環境保健の主たる研究目的であり, 途上国では金属鉱山・採掘や農薬撒布による健康リスクに関する研究が盛んにおこなわれているが, 先進国では環境による小児への健康影響に関心が向けられている. 1970年代後半に鉛による健康影響に関する論文が産業保健専門誌に多数掲載されるようになり, 世界保健機関(WHO)は1984年に水道水中の鉛指針値(WHO guideline value)を50μg/Lとした. 1993年には, この指針値を一気に10μg/Lに下げた(わが国の鉛の水質基準を50μg/L以下にしたのは1992年, 10μg/L以下になったのは2004年である).
AbstractList 「1. はじめに」環境保健はヒトの健康と環境の相互作用を解明する一学術分野である. 環境中に存在する有害因子(以下, 環境有害因子)には, 化学物質の曝露だけでなく, 廃棄物汚染, 越境汚染, 地球(および生活)環境変化に伴う温暖化(暑熱, 洪水・ゲリラ豪雨, 生物媒介感染症の拡大)や紫外線照射などが含まれる. これらがヒトの健康にどのような/どのように影響を与えるが環境保健の主たる研究目的であり, 途上国では金属鉱山・採掘や農薬撒布による健康リスクに関する研究が盛んにおこなわれているが, 先進国では環境による小児への健康影響に関心が向けられている. 1970年代後半に鉛による健康影響に関する論文が産業保健専門誌に多数掲載されるようになり, 世界保健機関(WHO)は1984年に水道水中の鉛指針値(WHO guideline value)を50μg/Lとした. 1993年には, この指針値を一気に10μg/Lに下げた(わが国の鉛の水質基準を50μg/L以下にしたのは1992年, 10μg/L以下になったのは2004年である).
Author 苅田, 香苗
村田, 勝敬
前田, 恵理
岩田, 豊人
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– reference: (36) Sampei M, Dakeishi M, Wood DC, Murata K. Impact of total sleep duration on blood pressure in preschool children. Biomed Res 2006;27:111–115.
– reference: (16) Strain JJ, Davidson PW, Bonham MP, Duffy EM, Stokes-Riner A, Thurston SW, Wallace JM, Robson PJ, Shamlaye CF, Georger LA, Sloane-Reeves J, Cernichiari E, Canfield RL, Cox C, Huang LS, Janciuras J, Myers GJ, Clarkson TW. Associations of maternal long-chain polyunsaturated fatty acids, methyl mercury, and infant development in the Seychelles child development nutrition study. Neurotoxicology 2008;29:776–782.
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– reference: (10) Sørensen N, Murata K, Budtz-Jørgensen E, Weihe P, Grandjean P. Prenatal methylmercury exposure as a cardiovascular risk factor at seven years of age. Epidemiology 1999;10:370–375.
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– reference: (1) International Programme on Chemical Safety. Environmental Health Criteria 165—Inorganic Lead. Geneva: World Health Organization, 1995.
– reference: (29) 苅田香苗,坂本峰至,吉田 稔,龍田 希,仲井邦彦,岩井美幸,岩田豊人,前田恵理,柳沼 梢,佐藤 洋,村田勝敬.メチル水銀,水銀およびセレンに関する研究動向―疫学研究を中心に―.日本衛生学雑誌2016;71:236–251.
– reference: (15) Myers GJ, Davidson PW, Cox C, Shamlaye CF, Palumbo D, Cernichiari E, Sloane-Reeves J, Wilding GE, Kost J, Huang LS, Clarkson TW. Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study. Lancet 2003;361:1686–1692.
– reference: (24) Sakamoto M, Chan HM, Domingo JL, Kubota M, Murata K. Changes in body burden of mercury, lead, arsenic, cadmium and selenium in infants during early lactation in comparison with placental transfer. Ecotoxicol Environ Saf 2012;84:179–184.
– reference: (45) EFSA. Use of the benchmark dose approach in risk assessment: guidance of the Scientific Committee. EFSA Journal 2009;1150:1–72.
– reference: (20) McMicheal AJ, Baghurst PA, Wigg NR, Vimpani GV, Robertson EF, Roberts RJ. Port Pirie cohort study: environmental exposure to lead and children’s abilities at the age of four years. N Engl J Med 1988;319:468–475.
– reference: (42) Grandjean P. Seven deadly sins of environmental epidemiology and the virtues of precaution. Epidemiology 2008;19:158–162.
– reference: (19) Tatsuta N, Murata K, Iwai-Shimada M, Yaginuma-Sakurai K, Satoh H, Nakai K. Psychomotor ability in children prenatally exposed to methylmercury: The 18-month follow-up of Tohoku study of child development. Tohoku J Exp Med 2017;242:1–8.
– reference: (3) Kawamoto T, Nitta H, Murata K, Toda E, Tsukamoto N, Hasegawa M, Yamagata Z, Kayama F, Kishi R, Ohya Y, Saito H, Sago H, Okuyama M, Ogata T, Yokoya S, Koresawa Y, Shibata Y, Nakayama S, Michikawa T, Takeuchi A, Satoh H, Working Group of the Epidemiological Research for Children’s Environmental Health. Rationale and study design of the Japan environmental and children’s study (JECS). BMC Public Health 2014;14:25.
– reference: (28) Hoenig JM, Heisey DM. The abuse of power: the pervasive fallacy of power calculations for data analysis. Am Stat 2001;55:19–24.
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Snippet 「1. はじめに」環境保健はヒトの健康と環境の相互作用を解明する一学術分野である. 環境中に存在する有害因子(以下, 環境有害因子)には, 化学物質の曝露だけでなく, 廃棄物...
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SubjectTerms リスク評価
出生コホート研究
環境保健研究
用量-反応関係
臨界濃度推定
Title 環境保健研究のジレンマ
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