随意筋収縮強度変化が体性感覚誘発磁界に及ぼす影響
「随意運動に伴う体性感覚誘発電位・体性感覚誘発磁界の減弱(Gating Effects)」 ヒトが随意運動を行う際には体性感覚情報の変化が生じることは周知の事実であるが, 中でも随意運動側と同側の末梢神経を刺激して体性感覚誘発電位(Somatosensory evoked potentials; SEPs)を記録すると, 安静時よりもSEP振幅値が減少するgatingが生じる. 哺乳類を対象とした研究において, 四肢の随意運動中では一次体性感覚野(Primary somatosensory cortex; S1)領域に存在する錐体細胞の興奮性が低下することが報告され, 随意運動中にS1へ求心性...
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| Published in | 日本基礎理学療法学雑誌 Vol. 21; no. 1; pp. 63 - 68 |
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| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本基礎理学療法学会
18.12.2018
Japanese Association of Physical Therapy Fundamentals |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2186-0742 2434-0731 |
| DOI | 10.24780/jptf.21.1_63 |
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| Abstract | 「随意運動に伴う体性感覚誘発電位・体性感覚誘発磁界の減弱(Gating Effects)」 ヒトが随意運動を行う際には体性感覚情報の変化が生じることは周知の事実であるが, 中でも随意運動側と同側の末梢神経を刺激して体性感覚誘発電位(Somatosensory evoked potentials; SEPs)を記録すると, 安静時よりもSEP振幅値が減少するgatingが生じる. 哺乳類を対象とした研究において, 四肢の随意運動中では一次体性感覚野(Primary somatosensory cortex; S1)領域に存在する錐体細胞の興奮性が低下することが報告され, 随意運動中にS1へ求心性入力が到達する前に末梢感覚情報の調節が行われることが示唆されている. 脳磁界計測装置(Magnetoencephalography; MEG)を用いた研究においてもSEPの報告と同様に, 随意運動中に末梢電気刺激を行った際には体性感覚誘発磁界(Somatosensory evoked fields; SEFs)のN20m, P35mが安静時と比較して減少することが報告されている. |
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| AbstractList | 「随意運動に伴う体性感覚誘発電位・体性感覚誘発磁界の減弱(Gating Effects)」 ヒトが随意運動を行う際には体性感覚情報の変化が生じることは周知の事実であるが, 中でも随意運動側と同側の末梢神経を刺激して体性感覚誘発電位(Somatosensory evoked potentials; SEPs)を記録すると, 安静時よりもSEP振幅値が減少するgatingが生じる. 哺乳類を対象とした研究において, 四肢の随意運動中では一次体性感覚野(Primary somatosensory cortex; S1)領域に存在する錐体細胞の興奮性が低下することが報告され, 随意運動中にS1へ求心性入力が到達する前に末梢感覚情報の調節が行われることが示唆されている. 脳磁界計測装置(Magnetoencephalography; MEG)を用いた研究においてもSEPの報告と同様に, 随意運動中に末梢電気刺激を行った際には体性感覚誘発磁界(Somatosensory evoked fields; SEFs)のN20m, P35mが安静時と比較して減少することが報告されている. Afferent somatosensory information is modulated before the afferent input arrives at the primary somatosensory cortex during voluntary movement. We investigated the changes in gating effect by muscular contraction strength and innervated and non-innervated muscles in human using 306-channel magnetoencephalography. SEFs were recorded following the right median nerve stimulation in a resting condition and during isometric muscular contractions from 10% electromyographic activity (EMG), 20% EMG, and 30% EMG of the right extensor indicis muscle and abductor pollicis brevis muscle. Our results showed that the equivalent current dipole (ECD) strength for P35m decreased with increasing strength of muscular contraction of the right abductor pollicis brevis muscle. However, changes were observed only at 30% EMG contraction level of the right extensor indicis muscle, which was not innervated by the median nerve. There were no significant changes in the peak latencies and ECD locations of each component in all conditions. The ECD strength did not differ significantly for N20m and P60m regardless of the strength of muscular contraction and innervation.Therefore, we suggest that the gating of SEF waveforms following peripheral nerve stimulation was affected by the strength of muscular contraction and innervation of the contracting muscle. |
| Author | 菅原, 和広 |
| Author_FL | Sugawara Kazuhiro |
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| DocumentTitleAlternate | Effect of muscle contraction strength on gating effect —An MEG study |
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| Snippet | 「随意運動に伴う体性感覚誘発電位・体性感覚誘発磁界の減弱(Gating Effects)」 ヒトが随意運動を行う際には体性感覚情報の変化が生じることは周知の事実であるが, 中でも随... Afferent somatosensory information is modulated before the afferent input arrives at the primary somatosensory cortex during voluntary movement. We... |
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| SubjectTerms | Gating effect Peripheral nerve stimulation Somatosensory evoked magnetic fields Strength of muscular contraction |
| Title | 随意筋収縮強度変化が体性感覚誘発磁界に及ぼす影響 |
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