心拍変動の高周波及び低周波成分の振幅変調にみられる長時間相関とその解釈

• Published in: Transactions of Japanese Society for Medical and Biological Engineering Vol. 54Annual; no. 27PM-Abstract; p. S217
• Main Authors: 早野, 順一郎, 鈴木, 康之, 山本, 義春, 清野, 健, 渡邉, 英一, 三木, 裕貴, 野村, 泰伸
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本生体医工学会 2016; Japanese Society for Medical and Biological Engineering
• ISSN: 1347-443X; 1881-4379
• DOI: 10.11239/jsmbe.54Annual.S217

Power spectral estimation of heart rate variability (HRV) has been widely employed to assess autonomic nervous system function. Among Power spectral-based indices, high-frequency (HF; 0.15 to 0.4 Hz) and low-frequency (LF; 0.04 to 0.15 Hz) band powers have most commonly been used; the physiological significance of these indices has also been extensively studied. However, nonlinear properties of HF and LF components have not been well understood. In this study, we investigated nonlinearity of HF and LF components in 122 healthy subjects and 108 patients with congestive heart failure (CHF). By analyzing bandpass-filtered time series of HRV corresponding to HF and LF components, it is shown that the amplitude modulations display long-range correlation indicating nonlinearity. Compared with the age-matched healthy controls, the CHF patients showed significantly decreased long-range correlation of HF amplitude modulation. Our findings suggest that nonlinearity of HF and LF components provides some complementary information on HRV dynamics.