mFOLFOX6療法後FOLFIRI療法時への切替における予防的制吐療法変更状況とその効果 進行・再発大腸がん患者を対象とした後方視的探索研究
「緒言」がん化学療法誘発性悪心・嘔吐(chemotherapy induced nausea and vomiting:CINV)は, 患者の感じる副作用として最もつらい症状の1つである. 治療意欲の低下を招き治療継続に支障をきたす可能性もあるため, CINV対策として適切な制吐療法を行うことが重要である. 海外ではThe Multinational Association of Supportive Care in Cancer(MASCC/ESMO)(http://www.mascc.org/assets/GuidelinesTools/mascc_antiemetic_english_2...
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| Published in | 医療薬学 Vol. 42; no. 3; pp. 185 - 192 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人日本医療薬学会
10.03.2016
日本医療薬学会 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1346-342X 1882-1499 |
| DOI | 10.5649/jjphcs.42.185 |
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| Abstract | 「緒言」がん化学療法誘発性悪心・嘔吐(chemotherapy induced nausea and vomiting:CINV)は, 患者の感じる副作用として最もつらい症状の1つである. 治療意欲の低下を招き治療継続に支障をきたす可能性もあるため, CINV対策として適切な制吐療法を行うことが重要である. 海外ではThe Multinational Association of Supportive Care in Cancer(MASCC/ESMO)(http://www.mascc.org/assets/GuidelinesTools/mascc_antiemetic_english_2014pdf, 2015年3月24日), American Society of Clinical Oncology(ASCO), 1)The National Comprehensive Cancer Network(NCCN)(http://www.nccn.org/professionals/physician_gls/pdf/antiemesis.pdf, 2015年3月25日)により制吐療法に関するガイドラインが公表されており, 中等度催吐性リスク化学療法(moderately emetogenic chemotherapy:MEC)に対しパロノセトロンとデキサメタゾンの併用が推奨されている. |
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| AbstractList | 「緒言」がん化学療法誘発性悪心・嘔吐(chemotherapy induced nausea and vomiting:CINV)は, 患者の感じる副作用として最もつらい症状の1つである. 治療意欲の低下を招き治療継続に支障をきたす可能性もあるため, CINV対策として適切な制吐療法を行うことが重要である. 海外ではThe Multinational Association of Supportive Care in Cancer(MASCC/ESMO)(http://www.mascc.org/assets/GuidelinesTools/mascc_antiemetic_english_2014pdf, 2015年3月24日), American Society of Clinical Oncology(ASCO), 1)The National Comprehensive Cancer Network(NCCN)(http://www.nccn.org/professionals/physician_gls/pdf/antiemesis.pdf, 2015年3月25日)により制吐療法に関するガイドラインが公表されており, 中等度催吐性リスク化学療法(moderately emetogenic chemotherapy:MEC)に対しパロノセトロンとデキサメタゾンの併用が推奨されている. |
| Author | 佐藤, 由美子 江尻, 将之 牛膓, 沙織 築山, 郁人 板倉, 由縁 森, 一博 小山, 佐知子 久田, 達也 荒川, 裕貴 |
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| References | 4) Hesketh PJ, Bosnjak SM, Nikolic V, Rapoport B, Incidence of delayed nausea and vomiting in patients with colorectal cancer receiving irinotecan-based chemotherapy, Support Care Cancer, 2011, 19, 2063-2066. 9) Tamura K, Aiba K, Saeki T, Nakanishi Y, Kamura T, Baba H, Yoshida K, Yamamoto N, Kitagawa Y, Maehara Y, Shimokawa M, Hirata K, Kitajima M, Testing the effectiveness of antiemetic guidelines:results of a prospective registry by the CINV Study Group of Japan, Int J Clin Oncol, DOI: 10.1007/s10147-015-0786-7. 8) Roscoe JA, Bushunow P, Morrow GR, Hickok JT, Kuebler PJ, Jacobs A, Banerjee TK, Patient expectation is a strong predictor of severe nausea after chemotherapy: a University of Rochester Community Clinical Oncology Program study of patients with breast carcinoma, Cancer, 2004, 101, 2701-2708. 10) Grunberg SM, Deuson RR, Mavros P, Geling O, Hansen M, Cruciani G, Daniele B, De Pouvourville G, Rubenstein EB, Daugaard G, Incidence of chemotherapy-induced and emesis after modern antiemetics: perception vs reality, Cancer, 2004, 100, 2261-2268. 1) Basch E, Prestrud AP, Hesketh PJ, Kris MG, Feyer PC, Somerfield MR, Chesney M, Clark-Snow RA, Flaherty AM, Freundlich B, Morrow G, Rao KV, Schwartz RN, Lyman GH, Antiemetics: American Society of Clinical Oncology clinical practice guideline update, J Clin Oncol, 2011, 29, 4189-4198. 2）日本癌治療学会編 “制吐薬適正使用ガイドライン”, 第1版, 金原出版, 東京, 2010, pp25-31. 6) Rapoport BL, Jordan K, Boice JA, Taylor A, Brown C, Hardwick JS, Carides A, Webb T, Schmoll H-J, Aprepiant for the prevention of chemotherapy-induced nausea and vomitimg associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, double-blind study, Support Care Cancer, 2010, 18, 423-431. 3) Hesketh PJ, Sanz-Altamira P, Bushey J, Hesketh AM, Prospective evaluation of the incidence of delayed nausea and vomiting in patients with colorectal cancer receiving oxaliplatin-based chemotherapy, Support Care Cancer, 2012, 20, 1043-1047. 5) Ueda H, Shimono C, Nishimura T, Shimamoto M, Yanaue H, Palonosetoron exahibits higher toral control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting, Molecular and Clinical Oncology, 2014, 2, 375-379. 7) Nishimura J, Satoh T, Fukunaga M, Takemoto H, Nakata K, Ide Y, Fukuzaki T, Kudo T, Miyake Y, Yasui M, Morita S, Sakai D, Uemura M, Hata T, Takemasa I, Mizushima T, Ohno Y, Yamamoto H, Sekimoto M, Nezu R, Doki Y, Mori M, Multi-center Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (MCSGO), Combination antiemetic therapy with aprepitant/fosaprepitant in patients with colorectal cancer receiving oxaliplatin-based chemotherapy (SENRI trial): a multicentre, randomised, controlled phase 3 trial, Eur J Cancer, 2015, 51, 1274-1282. |
| References_xml | – reference: 8) Roscoe JA, Bushunow P, Morrow GR, Hickok JT, Kuebler PJ, Jacobs A, Banerjee TK, Patient expectation is a strong predictor of severe nausea after chemotherapy: a University of Rochester Community Clinical Oncology Program study of patients with breast carcinoma, Cancer, 2004, 101, 2701-2708. – reference: 2）日本癌治療学会編 “制吐薬適正使用ガイドライン”, 第1版, 金原出版, 東京, 2010, pp25-31. – reference: 9) Tamura K, Aiba K, Saeki T, Nakanishi Y, Kamura T, Baba H, Yoshida K, Yamamoto N, Kitagawa Y, Maehara Y, Shimokawa M, Hirata K, Kitajima M, Testing the effectiveness of antiemetic guidelines:results of a prospective registry by the CINV Study Group of Japan, Int J Clin Oncol, DOI: 10.1007/s10147-015-0786-7. – reference: 5) Ueda H, Shimono C, Nishimura T, Shimamoto M, Yanaue H, Palonosetoron exahibits higher toral control rate compared to first-generation serotonin antagonists and improves appetite in delayed-phase chemotherapy-induced nausea and vomiting, Molecular and Clinical Oncology, 2014, 2, 375-379. – reference: 10) Grunberg SM, Deuson RR, Mavros P, Geling O, Hansen M, Cruciani G, Daniele B, De Pouvourville G, Rubenstein EB, Daugaard G, Incidence of chemotherapy-induced and emesis after modern antiemetics: perception vs reality, Cancer, 2004, 100, 2261-2268. – reference: 3) Hesketh PJ, Sanz-Altamira P, Bushey J, Hesketh AM, Prospective evaluation of the incidence of delayed nausea and vomiting in patients with colorectal cancer receiving oxaliplatin-based chemotherapy, Support Care Cancer, 2012, 20, 1043-1047. – reference: 4) Hesketh PJ, Bosnjak SM, Nikolic V, Rapoport B, Incidence of delayed nausea and vomiting in patients with colorectal cancer receiving irinotecan-based chemotherapy, Support Care Cancer, 2011, 19, 2063-2066. – reference: 7) Nishimura J, Satoh T, Fukunaga M, Takemoto H, Nakata K, Ide Y, Fukuzaki T, Kudo T, Miyake Y, Yasui M, Morita S, Sakai D, Uemura M, Hata T, Takemasa I, Mizushima T, Ohno Y, Yamamoto H, Sekimoto M, Nezu R, Doki Y, Mori M, Multi-center Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (MCSGO), Combination antiemetic therapy with aprepitant/fosaprepitant in patients with colorectal cancer receiving oxaliplatin-based chemotherapy (SENRI trial): a multicentre, randomised, controlled phase 3 trial, Eur J Cancer, 2015, 51, 1274-1282. – reference: 6) Rapoport BL, Jordan K, Boice JA, Taylor A, Brown C, Hardwick JS, Carides A, Webb T, Schmoll H-J, Aprepiant for the prevention of chemotherapy-induced nausea and vomitimg associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, double-blind study, Support Care Cancer, 2010, 18, 423-431. – reference: 1) Basch E, Prestrud AP, Hesketh PJ, Kris MG, Feyer PC, Somerfield MR, Chesney M, Clark-Snow RA, Flaherty AM, Freundlich B, Morrow G, Rao KV, Schwartz RN, Lyman GH, Antiemetics: American Society of Clinical Oncology clinical practice guideline update, J Clin Oncol, 2011, 29, 4189-4198. |
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| Snippet | 「緒言」がん化学療法誘発性悪心・嘔吐(chemotherapy induced nausea and vomiting:CINV)は, 患者の感じる副作用として最もつらい症状の1つである. 治療意欲の低下を招き治... |
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| SubjectTerms | antiemesis aprepitant chemotherapy-induced nausea and vomiting (CINV) dexamethasone moderately emetogenic chemotherapy (MEC) palonosetoron |
| Subtitle | 進行・再発大腸がん患者を対象とした後方視的探索研究 |
| Title | mFOLFOX6療法後FOLFIRI療法時への切替における予防的制吐療法変更状況とその効果 |
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