CLINICAL STUDY ON CS-807 IN RESPIRATORY INFECTIONS
A new oral cephem antibiotic, CS-807 was administered to 12 patients with respiratory infections, 10 of outpatients and 2 of inpatients. The drug was given a daily dose of 400mg, b. i. d. in 8 patients, 200mg, b. i. d. in 3 patients, and 300mg, t. i. d. in one patient for 5 to 14 days. The clinical...
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Published in | CHEMOTHERAPY Vol. 36; no. Supplement1; pp. 424 - 427 |
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Main Authors | , , , |
Format | Journal Article |
Language | English Japanese |
Published |
Japanese Society of Chemotherapy
1988
公益社団法人 日本化学療法学会 |
Online Access | Get full text |
ISSN | 0009-3165 1884-5894 |
DOI | 10.11250/chemotherapy1953.36.Supplement1_424 |
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Summary: | A new oral cephem antibiotic, CS-807 was administered to 12 patients with respiratory infections, 10 of outpatients and 2 of inpatients. The drug was given a daily dose of 400mg, b. i. d. in 8 patients, 200mg, b. i. d. in 3 patients, and 300mg, t. i. d. in one patient for 5 to 14 days. The clinical result was good in 8 cases and fair in 4 cases. In all cases, normalize of fever, WBC, CRP and ESR, and amelioration of sputum property and decrease of sputum volume were observed in several days after medication. Moreover, in 4 cases with pneumonia marked recovery of chest X-ray findings was found. Bacteriologically, isolates of S. aureus were eradicated in 3 cases and not evaluable in one case, and isolate of H. influenzae was decrease in one case. No side-effect was observed in all cases. Abnormal laboratory values were increase of eosinophile number and slightly elevated GOT, GPT in one case each. None were serious. |
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ISSN: | 0009-3165 1884-5894 |
DOI: | 10.11250/chemotherapy1953.36.Supplement1_424 |