Clinical study on ritipenem acoxil in ophthalmology

• Published in: Japanese Journal of Chemotherapy Vol. 43; no. Supplement3; pp. 572 - 573
• Main Authors: Hara, Jiro, Kawamura, Toshihiko, Yasuda, Fuyuko
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Chemotherapy 1995; 公益社団法人 日本化学療法学会
• Subjects: ritipenem acoxil; ペネム系抗菌剤; 前眼部感染症
• ISSN: 1340-7007; 1884-5886
• DOI: 10.11250/chemotherapy1995.43.Supplement3_572

Ritipenem acoxil, a new penem antibiotic for oral use, was administered to 12 patients with eye infections, including 2 patients with blepharitis, 6 with hordeolum, 1 with lid abscess, 2 with keratitis and 1 with dacryocystitis, at doses of 200 mg t. i. d. for 3-8 days. The clinical efficacy was excellent in 7 cases (58.3%), and the total clinical efficacy rate was 100%(12/12). Bacteriologically, the eradication rate was 83.3%(5/6). The only side effect was tiredness in only one patient. From the above results, we consider ritipenem acoxil to be a useful antimicrobial agent for anterior eye infections.