Pierre Robin Sequence児の呼吸管理方法の検討
Pierre Robin Sequence(以下PRSと略)は,小顎症に由来する舌根沈下,呼吸障害を主症状とする症状群であり,重症例では出生直後から呼吸管理を必要とすることもある.しかし,PRSの小顎症には明確な定義がないため,診断基準や呼吸管理方法にも未だ定まった見解があるとはいえない.今回われわれは,静岡県立こども病院形成外科を受診したPRS児36例の初診時日齢紹介理由,家族歴,合併症,入院時日齢,入院日数治療方針について遡及的に検討し,当院における呼吸管理方法の指針を検討した.口蓋裂は全例に合併していた.その他の合併症を持つPRS(s-PRSと略)児は9例(25.0%)と従来の報告とほぼ...
Saved in:
| Published in | 日本口蓋裂学会雑誌 Vol. 33; no. 3; pp. 280 - 289 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本口蓋裂学会
30.10.2008
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0386-5185 2186-5701 |
| DOI | 10.11224/cleftpalate1976.33.3_280 |
Cover
| Abstract | Pierre Robin Sequence(以下PRSと略)は,小顎症に由来する舌根沈下,呼吸障害を主症状とする症状群であり,重症例では出生直後から呼吸管理を必要とすることもある.しかし,PRSの小顎症には明確な定義がないため,診断基準や呼吸管理方法にも未だ定まった見解があるとはいえない.今回われわれは,静岡県立こども病院形成外科を受診したPRS児36例の初診時日齢紹介理由,家族歴,合併症,入院時日齢,入院日数治療方針について遡及的に検討し,当院における呼吸管理方法の指針を検討した.口蓋裂は全例に合併していた.その他の合併症を持つPRS(s-PRSと略)児は9例(25.0%)と従来の報告とほぼ一致していた.入院加療を必要とした症例は16例(44.4%)で,そのうち気管内挿管や外科的処置を必要とした症例は5例のみ(気管内挿管3例,うち1例が気管切開.舌固定,舌小帯切開を各1例)で,最近10年間は外科的処置を行っていなかった.保存的治療で管理した児と外科的処置を行った児の間では入院日数に有意差はなかった.s-PRS児と合併症のないPRS(ns-PRSと略)児の間で入院時日齢や入院日数に有意差はなかった.外科的処置を必要とする可能性が高いと考えられるs-PRS児の発生率はあまり高くないことと,大半の症例は保存的治療で症状が改善したことから,PRS児に対する呼吸管理方法は保存的治療を第一選択とすべきであると考えられた. |
|---|---|
| AbstractList | Pierre Robin Sequence(以下PRSと略)は,小顎症に由来する舌根沈下,呼吸障害を主症状とする症状群であり,重症例では出生直後から呼吸管理を必要とすることもある.しかし,PRSの小顎症には明確な定義がないため,診断基準や呼吸管理方法にも未だ定まった見解があるとはいえない.今回われわれは,静岡県立こども病院形成外科を受診したPRS児36例の初診時日齢紹介理由,家族歴,合併症,入院時日齢,入院日数治療方針について遡及的に検討し,当院における呼吸管理方法の指針を検討した.口蓋裂は全例に合併していた.その他の合併症を持つPRS(s-PRSと略)児は9例(25.0%)と従来の報告とほぼ一致していた.入院加療を必要とした症例は16例(44.4%)で,そのうち気管内挿管や外科的処置を必要とした症例は5例のみ(気管内挿管3例,うち1例が気管切開.舌固定,舌小帯切開を各1例)で,最近10年間は外科的処置を行っていなかった.保存的治療で管理した児と外科的処置を行った児の間では入院日数に有意差はなかった.s-PRS児と合併症のないPRS(ns-PRSと略)児の間で入院時日齢や入院日数に有意差はなかった.外科的処置を必要とする可能性が高いと考えられるs-PRS児の発生率はあまり高くないことと,大半の症例は保存的治療で症状が改善したことから,PRS児に対する呼吸管理方法は保存的治療を第一選択とすべきであると考えられた. |
| Author | 堀切, 将 松井, 貴浩 朴, 修三 |
| Author_FL | HORIKIRI Masaru PARK Susam MATSUI Takahiro |
| Author_FL_xml | – sequence: 1 fullname: HORIKIRI Masaru – sequence: 2 fullname: PARK Susam – sequence: 3 fullname: MATSUI Takahiro |
| Author_xml | – sequence: 1 fullname: 松井, 貴浩 organization: 静岡県立こども病院形成外科 – sequence: 1 fullname: 堀切, 将 organization: 静岡県立こども病院形成外科 – sequence: 1 fullname: 朴, 修三 organization: 静岡県立こども病院形成外科 |
| BackLink | https://cir.nii.ac.jp/crid/1571698601184228608$$DView record in CiNii |
| BookMark | eNpdkLtKA0EUhgeJYIx5hwi2G2fm7M6llOAlEFC81MPM7ozOEjdxdy0sLbSUWGhlI1hYpbFR8G0kiY_hhgiCzX9-fj5O8a2iWjbILELrBLcJoTTcjPvWlUPd16UlkrM2QBsUFXgJ1SkRLIg4JjVUxzDvREQrqFkUKcYYKDBOoY7Ygbd5bluHA-Oz1pG9uLRZbCc3o6_r8eT-czJ6n42fZ6Pb6ePH9O2hGqcvT9-vd2to2el-YZu_t4FOdraPO3tBb3-329nqBSkNqQh4DOCwNCJJGEgpndXYxJYlhoCGBEwiOVgMicHORIxq6oTFWoSSEU4chwbaWPzNvFexnyeJOGFSMEyICCmtiqiw7gJLi1KfWjXM_bnOr5TOS185Uv88KQAF86hU_TFnOlephh86n3HT |
| ContentType | Journal Article |
| Copyright | 一般社団法人 日本口蓋裂学会 |
| Copyright_xml | – notice: 一般社団法人 日本口蓋裂学会 |
| DBID | RYH |
| DOI | 10.11224/cleftpalate1976.33.3_280 |
| DatabaseName | CiNii Complete |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| DocumentTitleAlternate | Examination of Respiratory Management for Pierre Robin Sequence |
| DocumentTitle_FL | Examination of Respiratory Management for Pierre Robin Sequence |
| EISSN | 2186-5701 |
| EndPage | 289 |
| ExternalDocumentID | 10027091946 article_cleftpalate1976_33_3_33_280_article_char_ja |
| GroupedDBID | ALMA_UNASSIGNED_HOLDINGS JSP KQ8 RJT RYH |
| ID | FETCH-LOGICAL-j2428-7c33f09b8dd63999fea0bce6db13a3d3bd973e03db0fb562a2f8e0a8496171f73 |
| ISSN | 0386-5185 |
| IngestDate | Thu Jun 26 22:03:22 EDT 2025 Wed Sep 03 06:25:46 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Issue | 3 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j2428-7c33f09b8dd63999fea0bce6db13a3d3bd973e03db0fb562a2f8e0a8496171f73 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/cleftpalate1976/33/3/33_280/_article/-char/ja |
| PageCount | 10 |
| ParticipantIDs | nii_cinii_1571698601184228608 jstage_primary_article_cleftpalate1976_33_3_33_280_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2008-10-30 |
| PublicationDateYYYYMMDD | 2008-10-30 |
| PublicationDate_xml | – month: 10 year: 2008 text: 2008-10-30 day: 30 |
| PublicationDecade | 2000 |
| PublicationTitle | 日本口蓋裂学会雑誌 |
| PublicationTitleAlternate | 日口蓋誌 |
| PublicationYear | 2008 |
| Publisher | 一般社団法人 日本口蓋裂学会 |
| Publisher_xml | – name: 一般社団法人 日本口蓋裂学会 |
| References | 9) de Buys Roessingh, A. S., Herzog, G., Hohlfeld, J.: Respiratory distress in Pierre Robin: successful use of pharyngeal tube. J. Pediatr. Surg., 42: 1495-1499, 2007. 13) Pruzansky, S., Richmond, J. B.: Growth of mandible in infants with micrognathia. Am. J. Dis. Child., 117: 710-715, 1969. 7) Jones, K. L.: Robin sequence (Pierre Robin syndrome). In Jones, K. L., Smith D. W. ed; Smith's recognizable patterns of human malformation. 196-197, WB Saunders, Philadelphia, 1988. 3) Gordon, C. B., Manders, E. K.: Subacute and chronic respiratory obstruction. In Mathes, S. J. ed.; Plastic Surgery. Vol. 3, 763-797, E Saunders, Philadelphia, 2006. 17) Li, H. Y., Lo, L. J., Chen, K. S., et al.: Robin sequence: review of treatment modalities for airway obstruction in 110 casesInt. J. Pediatr. Otorhinolaryngol, 65: 45-51, 2002. 14) Laitinen, S. H., Ranta, R. E.: Cephalometric measurements in patients with Pierre Robin syndrome and isolated cleft palate. Scan. J. Plast. Reconstr. Surg. Hand. Surg., 26: 177-183, 1992. 2) Bartlett, S. P., Losee, J. E., Baker, S. B.: Pierre Robin Sequence. In Mathes, S. J. ed.; Plastic Surgery. Vol. 4, 511-515, E Saunders, Philadelphia, 2006. 1) Printzlau, A., Andersen, M.: Pierre Robin sequence in Denmark: a retrospective populationbased epidemiological study. Cleft Palate Craniofac. J., 41: 47-52, 2004. 19) Wagener, S., Rayatt, S. S., Tatman, A. J., et al.: Management of infants with Pierre Robin sequence. Cleft Palate Craniofac. J., 40: 180- 185, 2003. 15) Parsons, R. W., Smith, D. J.: Rule of thumb criteria for tongue-lip adhesion in Pierre Robin anomalad. Plast. Reconstr. Surg., 70: 210-212, 1982. 20) Cozzi, F., Totonelli, G., Frediani, S., et al.: The effect of glossopexy on weight velocity in infants with Pierre Robin syndrome. J. Pediatr. Surg., 43: 296-298, 2008. 6) de Buys Roessingh, A. S., Herzog, G., Cherpillod, J., et al.: Speech prognosis and need of pha- ryngeal flap for non syndromic vs syndromic Pierre Robin Sequence. J. Pediatr. Surg., 43 668-674, 2008. 10) Marques, I. L., de Sousa, T. V., Carneiro, A. F., et al.: Clinical experience with infants with Robin sequence: a prospective study. Cleft Palate Craniofac. J., 38: 171-178, 2001. 16) Anderson, K. D., Cole, A., Chuo, C. B., et al.: Home management of upper airway obstruction in Pierre Robin sequence using a nasopharyngeal airway. Cleft Palate Craniofac. J., 44: 269-273, 2007. 18) Heaf, D. P., Helms, P. J., Dinwiddie, R., et al.: Nasopharyngeal airways in Pierre Robin Syndrome. J. Pediatr., 100: 698-703, 1982. 22) Rawashdeh, M. A.: Transmandibular K-wire in the management of airway obstruction in Pierre Robin sequence. J. Craniofac. Surg., 15: 447-450, 2004. 4) Mitsukawa, N., Satoh, K, Suse, T. et al.: Clinical success of mandibular distraction for obstructive sleep apnea resulting from micrognathia in 10 consecutive Japanese young children. J. Craniofac. Surg., 18: 948-953, 2007. 5) Holder-Espinasse, M., Abadie, V., Cormier-Daire, V., et al.: Pierre Robin sequence: a series of 117 consecutive cases. J. Pediatr., 139: 588- 590, 2001. 11) Smith, J. L., Stowe, F. R.: The Pirre Robin syndrome (glossoptosis, micrognathia, cleft palate); A review of thirty nine cases with emphasis on associated oculoa lasions. Pediatrics, 27 128-133, 1961. 21) Caouette-Laberge, L., Plamondon, C., Larocque, Y.: Subperiosteal release of the floor of the mouth in Pierre Robin sequence: experience with 12 cases. Cleft Palate Craniofac. J., 33: 468-472, 1996. 8) Lidsky, M. E., Lander, T. A., Sidman, ID.: Resolving feeding difficulties with early airway intervention in Pierre Robin Sequence. Laryngoscope, 118: 120-123, 2008. 12) Abadie, V., Morisseau-Durand, M. P., Beyler, C., et al.: Brainstem disfunction: a possible neuroembryological pathomenesis of isolated Pierre Robin sequence. Eur. J. Pediatr., 161: 275-280, 2002. |
| References_xml | – reference: 3) Gordon, C. B., Manders, E. K.: Subacute and chronic respiratory obstruction. In Mathes, S. J. ed.; Plastic Surgery. Vol. 3, 763-797, E Saunders, Philadelphia, 2006. – reference: 6) de Buys Roessingh, A. S., Herzog, G., Cherpillod, J., et al.: Speech prognosis and need of pha- ryngeal flap for non syndromic vs syndromic Pierre Robin Sequence. J. Pediatr. Surg., 43 668-674, 2008. – reference: 18) Heaf, D. P., Helms, P. J., Dinwiddie, R., et al.: Nasopharyngeal airways in Pierre Robin Syndrome. J. Pediatr., 100: 698-703, 1982. – reference: 1) Printzlau, A., Andersen, M.: Pierre Robin sequence in Denmark: a retrospective populationbased epidemiological study. Cleft Palate Craniofac. J., 41: 47-52, 2004. – reference: 17) Li, H. Y., Lo, L. J., Chen, K. S., et al.: Robin sequence: review of treatment modalities for airway obstruction in 110 casesInt. J. Pediatr. Otorhinolaryngol, 65: 45-51, 2002. – reference: 21) Caouette-Laberge, L., Plamondon, C., Larocque, Y.: Subperiosteal release of the floor of the mouth in Pierre Robin sequence: experience with 12 cases. Cleft Palate Craniofac. J., 33: 468-472, 1996. – reference: 14) Laitinen, S. H., Ranta, R. E.: Cephalometric measurements in patients with Pierre Robin syndrome and isolated cleft palate. Scan. J. Plast. Reconstr. Surg. Hand. Surg., 26: 177-183, 1992. – reference: 22) Rawashdeh, M. A.: Transmandibular K-wire in the management of airway obstruction in Pierre Robin sequence. J. Craniofac. Surg., 15: 447-450, 2004. – reference: 8) Lidsky, M. E., Lander, T. A., Sidman, ID.: Resolving feeding difficulties with early airway intervention in Pierre Robin Sequence. Laryngoscope, 118: 120-123, 2008. – reference: 4) Mitsukawa, N., Satoh, K, Suse, T. et al.: Clinical success of mandibular distraction for obstructive sleep apnea resulting from micrognathia in 10 consecutive Japanese young children. J. Craniofac. Surg., 18: 948-953, 2007. – reference: 20) Cozzi, F., Totonelli, G., Frediani, S., et al.: The effect of glossopexy on weight velocity in infants with Pierre Robin syndrome. J. Pediatr. Surg., 43: 296-298, 2008. – reference: 16) Anderson, K. D., Cole, A., Chuo, C. B., et al.: Home management of upper airway obstruction in Pierre Robin sequence using a nasopharyngeal airway. Cleft Palate Craniofac. J., 44: 269-273, 2007. – reference: 7) Jones, K. L.: Robin sequence (Pierre Robin syndrome). In Jones, K. L., Smith D. W. ed; Smith's recognizable patterns of human malformation. 196-197, WB Saunders, Philadelphia, 1988. – reference: 13) Pruzansky, S., Richmond, J. B.: Growth of mandible in infants with micrognathia. Am. J. Dis. Child., 117: 710-715, 1969. – reference: 19) Wagener, S., Rayatt, S. S., Tatman, A. J., et al.: Management of infants with Pierre Robin sequence. Cleft Palate Craniofac. J., 40: 180- 185, 2003. – reference: 9) de Buys Roessingh, A. S., Herzog, G., Hohlfeld, J.: Respiratory distress in Pierre Robin: successful use of pharyngeal tube. J. Pediatr. Surg., 42: 1495-1499, 2007. – reference: 11) Smith, J. L., Stowe, F. R.: The Pirre Robin syndrome (glossoptosis, micrognathia, cleft palate); A review of thirty nine cases with emphasis on associated oculoa lasions. Pediatrics, 27 128-133, 1961. – reference: 5) Holder-Espinasse, M., Abadie, V., Cormier-Daire, V., et al.: Pierre Robin sequence: a series of 117 consecutive cases. J. Pediatr., 139: 588- 590, 2001. – reference: 2) Bartlett, S. P., Losee, J. E., Baker, S. B.: Pierre Robin Sequence. In Mathes, S. J. ed.; Plastic Surgery. Vol. 4, 511-515, E Saunders, Philadelphia, 2006. – reference: 12) Abadie, V., Morisseau-Durand, M. P., Beyler, C., et al.: Brainstem disfunction: a possible neuroembryological pathomenesis of isolated Pierre Robin sequence. Eur. J. Pediatr., 161: 275-280, 2002. – reference: 10) Marques, I. L., de Sousa, T. V., Carneiro, A. F., et al.: Clinical experience with infants with Robin sequence: a prospective study. Cleft Palate Craniofac. J., 38: 171-178, 2001. – reference: 15) Parsons, R. W., Smith, D. J.: Rule of thumb criteria for tongue-lip adhesion in Pierre Robin anomalad. Plast. Reconstr. Surg., 70: 210-212, 1982. |
| SSID | ssj0003236723 ssib002828992 |
| Score | 1.4873471 |
| Snippet | Pierre Robin Sequence(以下PRSと略)は,小顎症に由来する舌根沈下,呼吸障害を主症状とする症状群であり,重症例では出生直後から呼吸管理を必... |
| SourceID | nii jstage |
| SourceType | Publisher |
| StartPage | 280 |
| SubjectTerms | airway Pierre Robin Sequence respiratory management statistical examination エアウェイ 呼吸管理法 統計学的検討 |
| Title | Pierre Robin Sequence児の呼吸管理方法の検討 |
| URI | https://www.jstage.jst.go.jp/article/cleftpalate1976/33/3/33_280/_article/-char/ja https://cir.nii.ac.jp/crid/1571698601184228608 |
| Volume | 33 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本口蓋裂学会雑誌, 2008/10/30, Vol.33(3), pp.280-289 |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2186-5701 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0003236723 issn: 0386-5185 databaseCode: KQ8 dateStart: 19760101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR1NaxUxMLQVxIsoKlatPMGcyj6zm002OSavW4qiKLTQ27Kf2Ic8S3m9ePOgJ5F60JMXwYOnXrwo-G-krT_DmWS73foBWr2EvNnJZD6SzSRvM0PITUx-I5swD5pKqyAulA7AqZdBk7M4rlWjuEs2cfeeXFmLb6-L9ZnZF72vlranxbB88st7JSexKsDArnhL9i8s2xEFANTBvlCChaH8IxvfhzVtq150d7hg1vuPomkqqBJUM5py8BOpSRGiQ2pHrsKoVTRNEG5CrABESZpKqiW1GiuWUy16zSU1MdXQXFGjqEr7Hq1rCNSEq4yocb2oZWo44msgYl1DqET4yCxRA93FyI82NNVUW2QPcQxV3amto7dEbepwDXIEwwHRbERt7PgEavoIH34x_HID-wc2E48vqEUBj5EdIQH3FEgvOxljVIvPM9SdgriQtO0fOjhuD7EYcgFdoKwJ6sZ6HVsndKc_x7Y1i_-oot67msP4FqHPPjSsHQyzfQUiac9q2sXGR_1oJxXvrxw-oVXrhERe3p_XN_C4YFTCaGumm_kj0EYI_uSQ8yHPOgrHwoe3gzP7oUnGecaxgFZZh_Mw38rGsNs4FSVSYj6QOw96m1G3OY-6E0yOwf8in3-8lf40uXHI5a3f8Qiu3hg2PhjRYnaysdHz5lbPkbPtNmxgPEvnycw4v0Ckn08DN58Gh_Np79nO16e7e6--7O18Oth9d7DzfP_N5_2PrwG4__7ttw8vL5K15XR1tBK0eUWCMTikKkhKzhumC1VV6J_rps5ZUdayKkKe84oXlU54zXhVsKaA_UEeNapmuYo1uPthk_BLZG7yeFJfJgOeq0iXZVMw3cQ5qCDUtRCyZlKVrBJinlgvbLbpg8dkJ7DHPFkARWXlBpahwPhWSuKNcQzfJ5m68j86uUrOHM2ra2RuurVdL4C_PS2uu2HwHZbUqx4 |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pierre+Robin+Sequence%E5%85%90%E3%81%AE%E5%91%BC%E5%90%B8%E7%AE%A1%E7%90%86%E6%96%B9%E6%B3%95%E3%81%AE%E6%A4%9C%E8%A8%8E&rft.jtitle=%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%93%8B%E8%A3%82%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E6%9D%BE%E4%BA%95%2C+%E8%B2%B4%E6%B5%A9&rft.au=%E5%A0%80%E5%88%87%2C+%E5%B0%86&rft.au=%E6%9C%B4%2C+%E4%BF%AE%E4%B8%89&rft.date=2008-10-30&rft.pub=%E4%B8%80%E8%88%AC%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%93%8B%E8%A3%82%E5%AD%A6%E4%BC%9A&rft.issn=0386-5185&rft.eissn=2186-5701&rft.volume=33&rft.issue=3&rft.spage=280&rft.epage=289&rft_id=info:doi/10.11224%2Fcleftpalate1976.33.3_280&rft.externalDocID=article_cleftpalate1976_33_3_33_280_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0386-5185&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0386-5185&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0386-5185&client=summon |