下顎骨転移病変より確定診断が得られた甲状腺癌の1例
A follicular carcinoma of the thyroid can be difficult to differentiate from a follicular adenoma, a benign tumor of the thyroid, on the basis of histopathological findings. In such cases, the tumor is not diagnosed as malignant until distant metastasis develops. We report a case of follicular carci...
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Published in | 日本口腔外科学会雑誌 Vol. 59; no. 10; pp. 637 - 642 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
社団法人 日本口腔外科学会
20.10.2013
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Subjects | |
Online Access | Get full text |
ISSN | 0021-5163 2186-1579 |
DOI | 10.5794/jjoms.59.637 |
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Summary: | A follicular carcinoma of the thyroid can be difficult to differentiate from a follicular adenoma, a benign tumor of the thyroid, on the basis of histopathological findings. In such cases, the tumor is not diagnosed as malignant until distant metastasis develops. We report a case of follicular carcinoma of the thyroid that was definitively diagnosed when an osteolytic lesion developed in the right mandibular ramus. A 66-year-old woman visited our department because of gingival swelling at the posterior part of the right mandibular molar region. Diagnostic imaging revealed a mandibular lesion that had destroyed the inside of the bone and then progressed outward. In addition, a calcified lesion was found in the left lobe of the thyroid gland, and evidence suggesting multiple bone and lung metastases was also found. A biopsy of the mandibular lesion indicated that bone metastasis from a thyroid carcinoma was most likely. However, the histopathological diagnosis of the excised thyroid specimen was follicular adenoma, thus casting doubt on the possibility of metastasis from the mandibular lesion. A segmental resection of the mandible was performed as radical treatment for the mandibular lesion because it showed a trend toward enlargement. Histopathological examination of the resected lesion showed scant cellular atypia; however, it was definitively diagnosed as a follicular carcinoma of the thyroid on the basis of osteolytic findings in the specimen and distal metastasis to the mandible. |
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ISSN: | 0021-5163 2186-1579 |
DOI: | 10.5794/jjoms.59.637 |