口腔癌に対する逆行性動注化学放射線療法のカテーテル関連血流感染症に関する検討

Catheter-related bloodstream infection (CRBSI) is one of the serious complications of chemotherapy in various cancer treatments and often causes cessation or temporary withdrawal of treatment. We investigated CRBSIs associated with retrograde superselective intra-arterial chemoradiotherapy for oral...

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Published in日本口腔外科学会雑誌 Vol. 63; no. 4; pp. 178 - 184
Main Authors 小栗, 千里, 藤内, 祝, 光藤, 健司, 岩井, 俊憲, 廣田, 誠, 柴崎, 麻衣子, 中島, 英行, 根岸, 明秀, 小泉, 敏之, 來生, 知
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.04.2017
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.63.178

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Summary:Catheter-related bloodstream infection (CRBSI) is one of the serious complications of chemotherapy in various cancer treatments and often causes cessation or temporary withdrawal of treatment. We investigated CRBSIs associated with retrograde superselective intra-arterial chemoradiotherapy for oral cancer. A total of 160 patients with oral cancer who had received catheterization from the superficial temporal or occipital arteries to the tumor-feeding arteries in our institution between January 2010 and December 2014 were studied retrospectively. All intra-arterial catheter tips were sent for culture, and catheter bacterial cultures were positive in 67 patients (41.9%). Blood culture tests were performed in 50 patients who had fever with a temperature of 38℃ or higher, and blood cultures were positive in 20 patients (12.5%). Both catheter cultures and blood cultures were positive in 12 patients. The same bacteria were detected in 7 patients (4.4%), fulfilling the criteria for CRBSI. The incidence ratio of CRBSI was 0.83 per 1,000 catheter days. All CRBSIs were eventually controlled by appropriate antimicrobial therapy and catheter replacement or decannulation.
ISSN:0021-5163
2186-1579
DOI:10.5794/jjoms.63.178