歯肉病変より診断し得たWegener肉芽腫の1例

• Published in: 日本口腔外科学会雑誌 Vol. 59; no. 4; pp. 240 - 244
• Main Authors: 西久保, 周一, 小野田, 紀生, 河地, 誉, 田村, 英俊, 大金, 覚, 東郷, 拓也
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.04.2013
• Subjects: ウェゲナー肉芽腫; 自己免疫疾患; 顆粒状歯肉炎
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.59.240

Wegener's granulomatosis is a rare multi-system disease characterized by necrotic and granulomatous changes of the upper or lower respiratory tract and segmental necrotizing glomerulonephritis. Wegener's granulomatosis is considered a type of PR-3-ANCA-associated vasculitis. This disease is defined as an autoimmune disease. Only 2% of all patients develop Wegener's granulomatosis in the oral cavity, which is characterized by strawberry gums. We describe a patient with a painful gum ulcer in whom Wegener's granulomatosis was diagnosed at an early stage on the basis of clinical findings of internal medicine and gingival biopsy in collaboration with other departments.