多様な脳内マクロファージを理解する
The central nervous system (CNS) hosts a variety of immune cells including two anatomically and transcriptionally distinct macrophage populations: microglia are found in the parenchyma, whereas CNS border-associated macrophages (CAMs) cover the CNS interfaces, such as the perivascular spaces and the...
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| Published in | 日本薬理学会年会要旨集 p. 1-B-S07-1 |
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| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
公益社団法人 日本薬理学会
2023
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| Online Access | Get full text |
| ISSN | 2435-4953 |
| DOI | 10.1254/jpssuppl.97.0_1-B-S07-1 |
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| Summary: | The central nervous system (CNS) hosts a variety of immune cells including two anatomically and transcriptionally distinct macrophage populations: microglia are found in the parenchyma, whereas CNS border-associated macrophages (CAMs) cover the CNS interfaces, such as the perivascular spaces and the meninges. Recent emergence of novel genetic tools and cutting-edge techniques including single-cell RNA-seq enables to study the CNS macrophages in more depth and have given novel insights into the origins, kinetics, functions, transcriptomic profiles, heterogeneity of microglia and CAMs. In this symposium, I will discuss our current knowledge of the characteristics of CNS macrophages. |
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| Bibliography: | 97_1-B-S07-1 |
| ISSN: | 2435-4953 |
| DOI: | 10.1254/jpssuppl.97.0_1-B-S07-1 |