近赤外線装置を用いた副甲状腺の自家蛍光観察pde-neo®とFLUOBEAM 800®の比較

近赤外線装置を用いた副甲状腺の自家蛍光観察は,無侵襲で簡便に副甲状腺の探索や確認ができ,甲状腺手術あるいは副甲状腺手術に有用である。今回われわれは,副甲状腺の自家蛍光が観察可能な既製の2種類の近赤外線装置pde-neo®(浜松ホトニクス)/FLUOBEAM 800®(FLUOPTICS)を同一症例で使用し,性能の比較を行った。両機器ともに副甲状腺の自家蛍光は甲状腺より高く,両者の間で副甲状腺/甲状腺の蛍光輝度比に差はなかった。機器の特徴を比較した結果,切除組織からの自家移植目的での副甲状腺の探索にはpde-neo®が,術野における副甲状腺の探索にはFLUOBEAM 800®が優れていると思われ...

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Published in頭頸部外科 Vol. 30; no. 3; pp. 277 - 283
Main Authors 竹内, 美香, 高橋, 剛史, 太田, 久幸, 堀井, 新, 山崎, 恵介, 正道, 隆介, 植木, 雄志
Format Journal Article
LanguageJapanese
Published 特定非営利活動法人 日本頭頸部外科学会 2020
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ISSN1349-581X
1884-474X
DOI10.5106/jjshns.30.277

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Abstract 近赤外線装置を用いた副甲状腺の自家蛍光観察は,無侵襲で簡便に副甲状腺の探索や確認ができ,甲状腺手術あるいは副甲状腺手術に有用である。今回われわれは,副甲状腺の自家蛍光が観察可能な既製の2種類の近赤外線装置pde-neo®(浜松ホトニクス)/FLUOBEAM 800®(FLUOPTICS)を同一症例で使用し,性能の比較を行った。両機器ともに副甲状腺の自家蛍光は甲状腺より高く,両者の間で副甲状腺/甲状腺の蛍光輝度比に差はなかった。機器の特徴を比較した結果,切除組織からの自家移植目的での副甲状腺の探索にはpde-neo®が,術野における副甲状腺の探索にはFLUOBEAM 800®が優れていると思われた。
AbstractList 近赤外線装置を用いた副甲状腺の自家蛍光観察は,無侵襲で簡便に副甲状腺の探索や確認ができ,甲状腺手術あるいは副甲状腺手術に有用である。今回われわれは,副甲状腺の自家蛍光が観察可能な既製の2種類の近赤外線装置pde-neo®(浜松ホトニクス)/FLUOBEAM 800®(FLUOPTICS)を同一症例で使用し,性能の比較を行った。両機器ともに副甲状腺の自家蛍光は甲状腺より高く,両者の間で副甲状腺/甲状腺の蛍光輝度比に差はなかった。機器の特徴を比較した結果,切除組織からの自家移植目的での副甲状腺の探索にはpde-neo®が,術野における副甲状腺の探索にはFLUOBEAM 800®が優れていると思われた。
Author 竹内, 美香
正道, 隆介
植木, 雄志
太田, 久幸
堀井, 新
山崎, 恵介
高橋, 剛史
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11) Patel HP, Chadwick DR, Harrison BJ, et al: Systematic Review of Intravenous Methylene Blue in Parathyroid Surgery. Br J Surg 99:1345-1351, 2012.
16) McWade MA, Sanders ME, Broome JT, et al: Establishing the clinical utility of autofluorescence spectroscopy for parathyroid detection. Surgery 159:193-203, 2016.
4) Paras C, Keller M, White L, et al: Near-infrared autofluorescence for the detection of parathyroid glands. J Biomed Opt 16:67012-67014, 2011.
15) Kahramangil B, Dip F, Benmiloud F, et al: Detection of parathyroid autofluorescence using near-infrared imaging: a multicenter analysis of concordance between different surgeons. Ann Surg Oncol 1-6, 2018.
3) Zarebczan B, Chen H: Influence of surgical volume on operative failures for hyperparathyroidism. Adv Surg 45:237-248, 2011.
14) Kim SW, Song SH, Lee HS, et al: Intraoperative real-time localization of normal parathyroid glands with autofluorescence imaging. J Clin Endocrinol Metab 101:4646-4652, 2016.
8) Kose E, Rudin AV, Kaharamangil B, et al: Autofluorescence Imaging of Parathyroid Glands: An Assessment of Potential Indications. Surgery 167:173-179, 2020.
9) De Leeuw F, Breuskin I, Abbaci M, et al: Intraoperative Near-infrared Imaging for Parathyroid Gland Identification by Auto-fluorescence: A Feasibility Study. World J Surg 40:2131-2138, 2016.
13) McWade MA, Paras C, White LM, et al: Label-free intraoperative parathyroid localization with near-infrared autofluorescence imaging. J Clin Endocrinol Metab 99:4574-4580, 2014.
6) Squires MH, Jarvis R, Shirley LA, et al: Intraoperative Parathyroid Autofluorescence Detection in Patients with Primary Hyperparathyroidism. Ann Surg Oncol 26:1142-1148, 2019.
7) Idogawa H, Sakashita T, Homma A: A novel study for fluorescence patterns of the parathyroid glands during surgery using a fluorescence spectroscopy system [published online ahead of print, 2020 Feb 20]. Eur Arch Otorhinolaryngol.
1) Sosa JA, Bowman HM, Tielsch JM, et al: The importance of surgeon experience for clinical and economic outcomes from thyroidectomy. Ann Surg 228:320-330, 1998.
2) Erbil Y, Barbaros U, Ozbey N, et al: Risk factors of incidental parathyroidectomy after thyroidectomy for benign thyroid disorders. Int J Surg 7:58-61, 2009.
12) Suzuki T, Numata T, Shibuya M: Intraoperative photodynamic detection of normal parathyroid glands using 5-aminolevulinic acid. Laryngoscope 121:1462-1466, 2011.
10) Dip F, Falco J, Verna S, et al: Randomized Controlled Trial Comparing White Light with Near-Infrared Autofluorescence for Parathyroid Gland Identification During Total Thyroidectomy. J Am Coll Surg 228:744-751, 2019.
References_xml – reference: 11) Patel HP, Chadwick DR, Harrison BJ, et al: Systematic Review of Intravenous Methylene Blue in Parathyroid Surgery. Br J Surg 99:1345-1351, 2012.
– reference: 8) Kose E, Rudin AV, Kaharamangil B, et al: Autofluorescence Imaging of Parathyroid Glands: An Assessment of Potential Indications. Surgery 167:173-179, 2020.
– reference: 10) Dip F, Falco J, Verna S, et al: Randomized Controlled Trial Comparing White Light with Near-Infrared Autofluorescence for Parathyroid Gland Identification During Total Thyroidectomy. J Am Coll Surg 228:744-751, 2019.
– reference: 13) McWade MA, Paras C, White LM, et al: Label-free intraoperative parathyroid localization with near-infrared autofluorescence imaging. J Clin Endocrinol Metab 99:4574-4580, 2014.
– reference: 14) Kim SW, Song SH, Lee HS, et al: Intraoperative real-time localization of normal parathyroid glands with autofluorescence imaging. J Clin Endocrinol Metab 101:4646-4652, 2016.
– reference: 1) Sosa JA, Bowman HM, Tielsch JM, et al: The importance of surgeon experience for clinical and economic outcomes from thyroidectomy. Ann Surg 228:320-330, 1998.
– reference: 3) Zarebczan B, Chen H: Influence of surgical volume on operative failures for hyperparathyroidism. Adv Surg 45:237-248, 2011.
– reference: 15) Kahramangil B, Dip F, Benmiloud F, et al: Detection of parathyroid autofluorescence using near-infrared imaging: a multicenter analysis of concordance between different surgeons. Ann Surg Oncol 1-6, 2018.
– reference: 7) Idogawa H, Sakashita T, Homma A: A novel study for fluorescence patterns of the parathyroid glands during surgery using a fluorescence spectroscopy system [published online ahead of print, 2020 Feb 20]. Eur Arch Otorhinolaryngol.
– reference: 6) Squires MH, Jarvis R, Shirley LA, et al: Intraoperative Parathyroid Autofluorescence Detection in Patients with Primary Hyperparathyroidism. Ann Surg Oncol 26:1142-1148, 2019.
– reference: 9) De Leeuw F, Breuskin I, Abbaci M, et al: Intraoperative Near-infrared Imaging for Parathyroid Gland Identification by Auto-fluorescence: A Feasibility Study. World J Surg 40:2131-2138, 2016.
– reference: 4) Paras C, Keller M, White L, et al: Near-infrared autofluorescence for the detection of parathyroid glands. J Biomed Opt 16:67012-67014, 2011.
– reference: 2) Erbil Y, Barbaros U, Ozbey N, et al: Risk factors of incidental parathyroidectomy after thyroidectomy for benign thyroid disorders. Int J Surg 7:58-61, 2009.
– reference: 5) Shinden Y, Nakajo A, Arima H, et al: Intraoperative identification of the parathyroid gland with a fluorescence detection system. World J Surg 41:1506-1512, 2017.
– reference: 12) Suzuki T, Numata T, Shibuya M: Intraoperative photodynamic detection of normal parathyroid glands using 5-aminolevulinic acid. Laryngoscope 121:1462-1466, 2011.
– reference: 16) McWade MA, Sanders ME, Broome JT, et al: Establishing the clinical utility of autofluorescence spectroscopy for parathyroid detection. Surgery 159:193-203, 2016.
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SubjectTerms 副甲状腺
自家蛍光
近赤外線
Title 近赤外線装置を用いた副甲状腺の自家蛍光観察pde-neo®とFLUOBEAM 800®の比較
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