姿勢変化時の血圧調節における内耳前庭系の役割

• Published in: Transactions of Japanese Society for Medical and Biological Engineering Vol. 53; no. Supplement; p. S152_01
• Main Authors: 森田, 啓之, 安部, 力, 中村, 浩二, 田中, 邦彦
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本生体医工学会 2015; Japanese Society for Medical and Biological Engineering
• ISSN: 1347-443X; 1881-4379
• DOI: 10.11239/jsmbe.53.S152_01

The vestibular system is sensing posture or direction of the gravity. It has been known that it is playing important roles not only posture control, but also cardiovascular dynamics via the autonomic nervous system as output. The control system is playing important roles for controlling arterial pressure during posture change in human subjects. Changing the posture from supine to standing, body fluid shifts footward, and venous return or cardiac output is decreased. Without any control, arterial pressure should be decreased, but it is not changed largely in healthy subjects. However, arterial pressure is decreased when vestibular input is confused with galvanic vestibular stimulation (GVS). Thus, vestibular system is playing an important role for arterial at the onset of this standing. The change in arterial pressure at the onset of standing is correlated with balance of otolith function. Furthermore, GVS increases high frequency component which is a marker of parasympathetic nerve activity in heart rate variability. The increase is also correlated with change in arterial pressure at the onset of standing. The results suggest a presence of vestibulo-parasympathetic pathway.