Similar Outcomes of Cadarveric Kidney Transplantations Using Organs from Extended criteria donor and standard criteria donor

• Published in: Japanese Journal of Transplantation Vol. 58; no. Supplement; p. s126_2
• Main Authors: ISHII, YASUO, FUKUDA, MIRUZATO, YOKOYAMA, TAKAYOSHI, MIKI, KATSUYUKI, Yuki, Nakamura, KAMIYAMA, MANABU
• Format: Journal Article
• Language: English
• Published: The Japan Society for Transplantation 2023; 一般社団法人 日本移植学会
• ISSN: 0578-7947; 2188-0034
• DOI: 10.11386/jst.58.Supplement_s126_2

In kidney transplantation, ischemia-reperfusion injury results in a high rate of delayed graft function.Methods: Thirty patients underwent cadaveric kidney transplantation from January 2015 to July 2022. These patients were classified into two groups according to 12 patients received transplants from extended criteria donors(ECD) and 18 received them from standard criteria donors(SCD).Three of ECD group were preserved by machine perfusion. We used the CMP-X08 perfusion devise (Chuo Seiko Co.,Ltd) and Belzer MPS solution to preserve the donated organ.Results: Patient survival was observed for all patients. Renal function at 3months and 1year was better in SCD group. In ECD group, renal function at discharge and 3months better in simple cold storage(SCS), but renal function after 6months was better in hypothermic machine perfusion(HMP).There was no significant difference in graft survival between ECD and SCD. Conclusion: There were no significant differences in outcomes of our patients who received transplants from ECD or SCD. It was suggested that kidney transplantation with machine perfusion preservation for ECD group would maintain good renal function.