Improvement of solute removal efficiency in recirculating peritoneal dialysis (RPD)

• Published in: Jinko Zoki Vol. 26; no. 3; pp. 729 - 733
• Main Authors: FUKUI, K, SATO, Y, KANEKO, I, OTA, K, SUZUKI, S, HIROTANI, S, SANAKA, T, AGISHI, T, MINESHIMA, M, MASUDA, T
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1997; 一般社団法人 日本人工臓器学会
• Subjects: canine study; flushing; recirculating peritoneal dialysis; urea reduction rate; vibration
• ISSN: 0300-0818; 1883-6097
• DOI: 10.11392/jsao1972.26.729

In order to improve solute removal efficiency in peritoneal dialysis, three types of recirculating peritoneal dialysis (RPD) were introduced: (a) simple RPD, (b) vibrating RPD and (c) flushing RPD. Recirculating-dialysis experiments using dogs were carried out under 100 ml/min of flow for both recirculating and delivered dialysates during an ex vivo study in comparison with (d) the conventional continuous ambulatory peritoneal dialysis (CAPD). The urea reduction rates in a 4 hr experiments of a canine study were 12.7±6.2% (mean±S.D.) for (a), 20.5±5.3% for (b), 20.8±5.5% for (c) and 3.3±3.9% for (d). All RPD had a significantly higher reduction rate than CAPD. Type (c) RPD is most acceptable for clinical application because of its higher solute removal efficiency and reasonable from economical aspects.