MATERIAL DESIGN OF HIGHLY-SELECTIVE ADSORBENT FOR SEPARATION OF LYMPHOCYTE SUBPOPULATIONS

Adhesiveness of lymphocyte subpopulations to the adsorbents with affinity substances was investigated for carrying out therapy such as cytapheresis, LAK, transplantation or immunological diagnosis. B lymphocytes adhered selectively to the adsorbents with polysaccharides containing abandant hydrogen...

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Bibliographic Details
Published inJinko Zoki Vol. 19; no. 2; pp. 958 - 961
Main Authors NAGOYA, M., YAMAMOTO, Y., YURA, H., AKAIKE, T., TAKAHASHI, A.
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1990
一般社団法人 日本人工臓器学会
Subjects
adsorbent
glycolipid
lymphocyte subpopulation
polysaccharide
separation
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ISSN0300-0818
1883-6097
DOI10.11392/jsao1972.19.958

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Summary:Adhesiveness of lymphocyte subpopulations to the adsorbents with affinity substances was investigated for carrying out therapy such as cytapheresis, LAK, transplantation or immunological diagnosis. B lymphocytes adhered selectively to the adsorbents with polysaccharides containing abandant hydrogen bonding sites, and T lymphocytes (CD4 (+) and CD8 (+) cells) were preferentially attached to the adsorbents immobilizing glycolipids via hydrophobic bond.
ISSN:0300-0818
1883-6097
DOI:10.11392/jsao1972.19.958