Analysis of the Calcified Materials from Calcinosis Cutis

• Published in: Japanese Journal of Clinical Chemistry Vol. 32; no. 3; pp. 249 - 254
• Main Authors: Kikyo, Shinzo, Aita, Saburo, Muraishi, Shuichi, Inoue, Tatsuya, Konno, Minoru, Ando, Kazuto
• Format: Journal Article
• Language: Japanese
• Published: Japan Society of Clinical Chemistry 2003; 一般社団法人 日本臨床化学会
• Subjects: amorphous; calcified materials; calcinosis cutis; calcium carbonate; calcium phosphate compound; hydroxyapatite crystal; ハイドロキシアパタイト結晶; リン酸カルシウム; 炭酸カルシウム; 皮膚石灰沈着症; 石灰化物質; 非晶性
• ISSN: 0370-5633; 2187-4077
• DOI: 10.14921/jscc1971b.32.3_249

We analyzed the calcified materials from ten cases of calcinosis cutis. All of the calcified materials were identified as hydroxyapatite (HA) by X-ray diffraction examination. However, Fourier transform infrared and Raman spectral analysis of these specimens showed that each contained calcium phosphate and calcium carbonate. We also detected carbonate in these specimens by total carbon analysis. Therefore, we concluded that the components of these calcified materials were mainly crystalline HA and amorphous calcium carbonate.