聴性脳幹反応における有意差検定脳電図に関する研究

1) 正常者5名において平均加算時の振幅と位相のバラツキが最小限となるようにディジタルフィルタの帯域幅を400-1520Hzに設定し, topography作成に必要な安定した再現性のあるABR波形を記録できた. 2) 正常者30名におけるABRの潜時, 振幅, 面積の正規性と個体間の変動の検討から, P I波, P III波, P V波潜時およびそれらの頂点間潜時, P I波, P III波, P V波, N III波, NV波およびIII波, V波振幅, P III波, P V波, N III波, NV波およびIII波, IV/V波面積を有意差検定脳電図 (SPM) の適切な指標として選択...

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Published in耳鼻と臨床 Vol. 38; no. 3; pp. 200 - 213
Main Author 木村, 謙一
Format Journal Article
LanguageJapanese
Published 耳鼻と臨床会 1992
Subjects
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ISSN0447-7227
2185-1034
DOI10.11334/jibi1954.38.3_200

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Abstract 1) 正常者5名において平均加算時の振幅と位相のバラツキが最小限となるようにディジタルフィルタの帯域幅を400-1520Hzに設定し, topography作成に必要な安定した再現性のあるABR波形を記録できた. 2) 正常者30名におけるABRの潜時, 振幅, 面積の正規性と個体間の変動の検討から, P I波, P III波, P V波潜時およびそれらの頂点間潜時, P I波, P III波, P V波, N III波, NV波およびIII波, V波振幅, P III波, P V波, N III波, NV波およびIII波, IV/V波面積を有意差検定脳電図 (SPM) の適切な指標として選択した. 3) ABRのSPMを小脳橋角部腫瘍と橋部腫瘍の2症例に応用し, 潜時の異常が限局した部位に見られたり振幅や面積の異常を示す部位が各波によって異なるなど, 単一誘導では観察できない情報が得られた. 以上から, 従来困難視されていたABRtopographyにおけるSPMが作成され, 機能的画像診断として臨床応用可能と考えた.
AbstractList 1) 正常者5名において平均加算時の振幅と位相のバラツキが最小限となるようにディジタルフィルタの帯域幅を400-1520Hzに設定し, topography作成に必要な安定した再現性のあるABR波形を記録できた. 2) 正常者30名におけるABRの潜時, 振幅, 面積の正規性と個体間の変動の検討から, P I波, P III波, P V波潜時およびそれらの頂点間潜時, P I波, P III波, P V波, N III波, NV波およびIII波, V波振幅, P III波, P V波, N III波, NV波およびIII波, IV/V波面積を有意差検定脳電図 (SPM) の適切な指標として選択した. 3) ABRのSPMを小脳橋角部腫瘍と橋部腫瘍の2症例に応用し, 潜時の異常が限局した部位に見られたり振幅や面積の異常を示す部位が各波によって異なるなど, 単一誘導では観察できない情報が得られた. 以上から, 従来困難視されていたABRtopographyにおけるSPMが作成され, 機能的画像診断として臨床応用可能と考えた.
Author 木村, 謙一
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References 7) 細川智: 中枢性神経系疾患の聴性脳幹反応について. 日耳鼻82: 11-26, 1979.
31) Stokard JE et al: Brainstem auditory-evoked responses. Normal variation as a function of stimuus and subject characteristics. Arch Neurol 36: 823-831, 1979.
12) 曽田豊二他: 聴性誘発反応の頭皮上トポグラフィ. 二次元脳電図の臨床. 131-140頁, にゅーろん社, 東京, 1984.
23) Chiappa KH et al: Brain stem auditory evoked resposes. Studies of waveform variations in 50 normal human subjects. Arch Neurol 36: 81-87, 1979.
4) Sanders RA et al: Clinical experience with brain stem audiometry performed under general anesthesia. J Otolaryngol 8: 24-32, 1979.
16) Lauter JL and Loomis RL: Individual differences in auditory electric responses. Comparisons of between-subject and within-subject variability. II. Amplitude of brainstem vertex-positive peaks. Scand Audiol 17: 87-92, 1988.
19) 白石君男他: 基準電極部位のABR波形におよぼす影響について. 耳鼻32補: 1155-1161, 1986.
38) 下河内稔: 誘発電位の臨床検査指針〔2〕(米国脳波学会, 1984), 臨床脳波30: 557-559, 1988.
14) 曽田豊二他: ABRトポグラフィー. JOHNS 5: 392-335, 1989.
37) 下河内稔: 誘発電位の臨床検査指針〔1〕(米国脳波学会, 1984). 臨床脳波30: 481-485, 1988.
42) Psatta DM et al: Age-dependent amplitude variation of brain-stem auditory evoked potentials. Electroencephalogr Clin Neurophysiol 71: 27-32, 1988.
41) 木村謙一他: ABR topographyのSPM (significance probability mapping) の検討. Audiology Japan 30: 389-390, 1987.
18) Duffy FH et al: Significance probability mapping. an aid in the topographic analysis of brain electrical activity. Electroencephalogr Clin Neurophysiol 51: 455-462, 1981.
15) Lauter JL and Loomis RL: Individual differences in auditory electric responses. Comparisons of between-subject and within-subject variability. I Absolute latencies of brainstem vertex-positive peaks. Scand Audiol 15: 167-172, 1986.
9) 上野照剛: 脳波および脳磁場の生成伝播モデル. 二次元脳電図の臨床. 41-50頁, にゅーろん社, 東京, 1984.
32) 曽田豊二他: 聴性誘発反応のトポグラフィーについて. 耳鼻24: 571-583, 1978.
22) 木村謙一他: SPM処理に際してのABR波形の検討. Audiology Japan 31: 387-388, 1988.
24) McGee T et al: Toward a strategy for analyzing the auditory middle-latency response waveform. Audiology 27: 119-130, 1988.
27) Allison T et al: Brain stem auditory, patternreversal visual, and short-latency somatosensory evoked potensials. Latencies in relation to age, sex, and brain and body size. Electroencenha lour Clin Npnrnnhysinl 55: 619-636, 1983.
8) 曽田豊二他: 聴神経腫瘍ならびに小脳橋角部腫瘍症例におけるABR. 耳鼻30: 808-817, 1984.
10) 江浦陽一: 正常乳幼児における聴性脳幹反応の頭皮上電位分布の研究. 耳鼻32補: 1136-1154, 1986.
28) 深谷卓他: ABR潜時と頭位径の関係. Audiology Japan 31: 744-746, 1988.
3) Kjaer M: Recongnizability of brain stem auditory evoked potential components. Acta Neurol Scand 62: 20-33, 1980.
6) Stokard JJ et at: Nonpathologic factors influencing brainstem auditory evoked potentials. Am T EEG Technol 18: 177-209. 1978.
13) Soda T et al: Latency distribition of auditory brainstem responses on human scalp. Clinical Topographic Electroencephaloglaphy and Evoked Potential, pp157-164, Shindan-to-Chiryo Co, Tokyo, 1986.
25) 辻達彦: 確率と理論的度数分布-医学・歯学・パラメジカル-統計方法入門. 47-60頁, 金原出版, 東京, 1981.
36) 鈴木篤郎他: 聴性脳幹反応の周波数分析. 刺激強度および刺激間隔と反応周波数成分との関係, Audiology Japan 25: 631-635, 1982.
2) Chan YW et al: The intraction between sex and click polarity in brain-stem auditory potentials evoked from control subjects of Oriental and Caucasian origin. Electroencephalogr Clin Neurophysiol 71: 77-80, 1988.
5) 白石君男他: 聴性誘発脳幹反応の電位地図に関与するフィルタの検討. Audiology Japan23: 233-234, 1980.
29) Jerger J et al: Effects of age and sex on auditory brainstem response. Arch Otolaryngol 106: 387-391, 1980.
39) Hamid OA et al: A proposed method to evaluate brain stem auditory evoked potential amplitude: pilot study. Am J Otol 7: 333-337, 1986.
11) 松田俊一: ヒトの聴性脳幹反応の頭皮上電位分布および潜時分布に関する研究. 耳鼻32補: 1121-1135, 1986.
43) Rosenhall U et al: Brain-stem auditory evoked potentials in different age groups. Electroencephalogr Clin Neurophysiol 62: 426-430, 1985.
21) Hyde ML: Instrumentation and signal processing. The Auditory Brainstem Response. pp33-48, Taylor & Francis Ltd, London, 1985.
20) Shiraishi K et al: Significance of reference electrode position in the recording of auditory brainstrem response. EEG TOPOGRAPHY 1987. pp113-140, NEURON Publishing Co, Tokyo, 1988.
1) Jewett DL et al: Auditory-evoked far fields averaged from the scalp of humans. Brain 94: 681-696, 1971.
34) 木村謙一他: 乳幼児ABRのパワースペクトル分析. 日耳鼻90: 1519-1520, 1987.
26) 石川栄助: 歪度と尖度による正規性の検定. 実務家のための新統計学. 196-201頁, 槇書店, 東京, 1983.
33) Fridmal J et al: Application of digital filtering and automatic peak detection to barin stem auditory evoked potential. Electroencephalogr Clin Neurophysiol 53: 405-416, 1982.
40) Thivierge J et al: Brainstem auditory evoked responces (BAER). normative study in children and adults. Electroencephalogr Clin Neurophysiol 68: 479-484, 1989.
44) Rowe MJ III: Normal variability of the brainstem auditory evoked response in young and old adult subjects. Electroencephalogr Clin Neurophysiol 44: 495-470, 1978.
35) 鈴木篤郎他: 聴性脳幹反応の周波数分析. Audiology Japan 24: 173-177, 1981.
17) 青柳優: 聴性電気反応検査におけるフーリエ変換法利用の現況. 日耳鼻89: 478-490, 1986.
30) Maurizi M et al: Effect of sex on auditory brainstem responses in infancy and early childhood. Scand Audiol 17: 143-146, 1988.
References_xml – reference: 2) Chan YW et al: The intraction between sex and click polarity in brain-stem auditory potentials evoked from control subjects of Oriental and Caucasian origin. Electroencephalogr Clin Neurophysiol 71: 77-80, 1988.
– reference: 20) Shiraishi K et al: Significance of reference electrode position in the recording of auditory brainstrem response. EEG TOPOGRAPHY 1987. pp113-140, NEURON Publishing Co, Tokyo, 1988.
– reference: 5) 白石君男他: 聴性誘発脳幹反応の電位地図に関与するフィルタの検討. Audiology Japan23: 233-234, 1980.
– reference: 7) 細川智: 中枢性神経系疾患の聴性脳幹反応について. 日耳鼻82: 11-26, 1979.
– reference: 15) Lauter JL and Loomis RL: Individual differences in auditory electric responses. Comparisons of between-subject and within-subject variability. I Absolute latencies of brainstem vertex-positive peaks. Scand Audiol 15: 167-172, 1986.
– reference: 29) Jerger J et al: Effects of age and sex on auditory brainstem response. Arch Otolaryngol 106: 387-391, 1980.
– reference: 18) Duffy FH et al: Significance probability mapping. an aid in the topographic analysis of brain electrical activity. Electroencephalogr Clin Neurophysiol 51: 455-462, 1981.
– reference: 1) Jewett DL et al: Auditory-evoked far fields averaged from the scalp of humans. Brain 94: 681-696, 1971.
– reference: 28) 深谷卓他: ABR潜時と頭位径の関係. Audiology Japan 31: 744-746, 1988.
– reference: 38) 下河内稔: 誘発電位の臨床検査指針〔2〕(米国脳波学会, 1984), 臨床脳波30: 557-559, 1988.
– reference: 6) Stokard JJ et at: Nonpathologic factors influencing brainstem auditory evoked potentials. Am T EEG Technol 18: 177-209. 1978.
– reference: 3) Kjaer M: Recongnizability of brain stem auditory evoked potential components. Acta Neurol Scand 62: 20-33, 1980.
– reference: 11) 松田俊一: ヒトの聴性脳幹反応の頭皮上電位分布および潜時分布に関する研究. 耳鼻32補: 1121-1135, 1986.
– reference: 31) Stokard JE et al: Brainstem auditory-evoked responses. Normal variation as a function of stimuus and subject characteristics. Arch Neurol 36: 823-831, 1979.
– reference: 13) Soda T et al: Latency distribition of auditory brainstem responses on human scalp. Clinical Topographic Electroencephaloglaphy and Evoked Potential, pp157-164, Shindan-to-Chiryo Co, Tokyo, 1986.
– reference: 24) McGee T et al: Toward a strategy for analyzing the auditory middle-latency response waveform. Audiology 27: 119-130, 1988.
– reference: 17) 青柳優: 聴性電気反応検査におけるフーリエ変換法利用の現況. 日耳鼻89: 478-490, 1986.
– reference: 14) 曽田豊二他: ABRトポグラフィー. JOHNS 5: 392-335, 1989.
– reference: 44) Rowe MJ III: Normal variability of the brainstem auditory evoked response in young and old adult subjects. Electroencephalogr Clin Neurophysiol 44: 495-470, 1978.
– reference: 36) 鈴木篤郎他: 聴性脳幹反応の周波数分析. 刺激強度および刺激間隔と反応周波数成分との関係, Audiology Japan 25: 631-635, 1982.
– reference: 39) Hamid OA et al: A proposed method to evaluate brain stem auditory evoked potential amplitude: pilot study. Am J Otol 7: 333-337, 1986.
– reference: 10) 江浦陽一: 正常乳幼児における聴性脳幹反応の頭皮上電位分布の研究. 耳鼻32補: 1136-1154, 1986.
– reference: 27) Allison T et al: Brain stem auditory, patternreversal visual, and short-latency somatosensory evoked potensials. Latencies in relation to age, sex, and brain and body size. Electroencenha lour Clin Npnrnnhysinl 55: 619-636, 1983.
– reference: 32) 曽田豊二他: 聴性誘発反応のトポグラフィーについて. 耳鼻24: 571-583, 1978.
– reference: 33) Fridmal J et al: Application of digital filtering and automatic peak detection to barin stem auditory evoked potential. Electroencephalogr Clin Neurophysiol 53: 405-416, 1982.
– reference: 37) 下河内稔: 誘発電位の臨床検査指針〔1〕(米国脳波学会, 1984). 臨床脳波30: 481-485, 1988.
– reference: 40) Thivierge J et al: Brainstem auditory evoked responces (BAER). normative study in children and adults. Electroencephalogr Clin Neurophysiol 68: 479-484, 1989.
– reference: 12) 曽田豊二他: 聴性誘発反応の頭皮上トポグラフィ. 二次元脳電図の臨床. 131-140頁, にゅーろん社, 東京, 1984.
– reference: 16) Lauter JL and Loomis RL: Individual differences in auditory electric responses. Comparisons of between-subject and within-subject variability. II. Amplitude of brainstem vertex-positive peaks. Scand Audiol 17: 87-92, 1988.
– reference: 42) Psatta DM et al: Age-dependent amplitude variation of brain-stem auditory evoked potentials. Electroencephalogr Clin Neurophysiol 71: 27-32, 1988.
– reference: 22) 木村謙一他: SPM処理に際してのABR波形の検討. Audiology Japan 31: 387-388, 1988.
– reference: 35) 鈴木篤郎他: 聴性脳幹反応の周波数分析. Audiology Japan 24: 173-177, 1981.
– reference: 4) Sanders RA et al: Clinical experience with brain stem audiometry performed under general anesthesia. J Otolaryngol 8: 24-32, 1979.
– reference: 8) 曽田豊二他: 聴神経腫瘍ならびに小脳橋角部腫瘍症例におけるABR. 耳鼻30: 808-817, 1984.
– reference: 41) 木村謙一他: ABR topographyのSPM (significance probability mapping) の検討. Audiology Japan 30: 389-390, 1987.
– reference: 21) Hyde ML: Instrumentation and signal processing. The Auditory Brainstem Response. pp33-48, Taylor & Francis Ltd, London, 1985.
– reference: 25) 辻達彦: 確率と理論的度数分布-医学・歯学・パラメジカル-統計方法入門. 47-60頁, 金原出版, 東京, 1981.
– reference: 30) Maurizi M et al: Effect of sex on auditory brainstem responses in infancy and early childhood. Scand Audiol 17: 143-146, 1988.
– reference: 23) Chiappa KH et al: Brain stem auditory evoked resposes. Studies of waveform variations in 50 normal human subjects. Arch Neurol 36: 81-87, 1979.
– reference: 19) 白石君男他: 基準電極部位のABR波形におよぼす影響について. 耳鼻32補: 1155-1161, 1986.
– reference: 43) Rosenhall U et al: Brain-stem auditory evoked potentials in different age groups. Electroencephalogr Clin Neurophysiol 62: 426-430, 1985.
– reference: 26) 石川栄助: 歪度と尖度による正規性の検定. 実務家のための新統計学. 196-201頁, 槇書店, 東京, 1983.
– reference: 9) 上野照剛: 脳波および脳磁場の生成伝播モデル. 二次元脳電図の臨床. 41-50頁, にゅーろん社, 東京, 1984.
– reference: 34) 木村謙一他: 乳幼児ABRのパワースペクトル分析. 日耳鼻90: 1519-1520, 1987.
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Snippet 1) 正常者5名において平均加算時の振幅と位相のバラツキが最小限となるようにディジタルフィルタの帯域幅を400-1520Hzに設定し, topography作成に必要な安定した再現...
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聴性脳幹反応 (ABR)
Title 聴性脳幹反応における有意差検定脳電図に関する研究
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