頭蓋骨縫合早期癒合症の診断と治療―現状と課題
頭蓋骨縫合早期癒合症は, 頭蓋骨縫合だけが早期癒合する単純型と顔面骨早期癒合, 指趾異常 (合指趾, 幅広拇趾など), 関節拘縮, 長管骨癒合, 眼瞼下垂などを伴う症候群がある. 罹患縫合が単一の場合, 複数の場合があり, 頭蓋形態も種々で多様性に富む疾患である. 発育途中の頭蓋骨を治療するため, 年齢, 頭蓋形態により手術方法が異なり, 治療のコンセンサスは確立されていない. 骨延長法や頭蓋形成ヘルメットなど, 低侵襲に良好な頭蓋形態を得るための手術法は進歩しているが, 未解決の課題も多い. 本論文では, ①治療の歴史的変遷, ②治療の現状と課題, ③治療戦略のアルゴリズム, ④病態解明と予...
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| Published in | 脳神経外科ジャーナル Vol. 28; no. 4; pp. 197 - 204 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本脳神経外科コングレス
2019
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0917-950X 2187-3100 |
| DOI | 10.7887/jcns.28.197 |
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| Abstract | 頭蓋骨縫合早期癒合症は, 頭蓋骨縫合だけが早期癒合する単純型と顔面骨早期癒合, 指趾異常 (合指趾, 幅広拇趾など), 関節拘縮, 長管骨癒合, 眼瞼下垂などを伴う症候群がある. 罹患縫合が単一の場合, 複数の場合があり, 頭蓋形態も種々で多様性に富む疾患である. 発育途中の頭蓋骨を治療するため, 年齢, 頭蓋形態により手術方法が異なり, 治療のコンセンサスは確立されていない. 骨延長法や頭蓋形成ヘルメットなど, 低侵襲に良好な頭蓋形態を得るための手術法は進歩しているが, 未解決の課題も多い. 本論文では, ①治療の歴史的変遷, ②治療の現状と課題, ③治療戦略のアルゴリズム, ④病態解明と予防に向けた研究の現状について述べる. |
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| AbstractList | 頭蓋骨縫合早期癒合症は, 頭蓋骨縫合だけが早期癒合する単純型と顔面骨早期癒合, 指趾異常 (合指趾, 幅広拇趾など), 関節拘縮, 長管骨癒合, 眼瞼下垂などを伴う症候群がある. 罹患縫合が単一の場合, 複数の場合があり, 頭蓋形態も種々で多様性に富む疾患である. 発育途中の頭蓋骨を治療するため, 年齢, 頭蓋形態により手術方法が異なり, 治療のコンセンサスは確立されていない. 骨延長法や頭蓋形成ヘルメットなど, 低侵襲に良好な頭蓋形態を得るための手術法は進歩しているが, 未解決の課題も多い. 本論文では, ①治療の歴史的変遷, ②治療の現状と課題, ③治療戦略のアルゴリズム, ④病態解明と予防に向けた研究の現状について述べる. |
| Author | 赤井, 卓也 山下, 昌信 黒田, 敏 飯塚, 秀明 |
| Author_xml | – sequence: 1 fullname: 山下, 昌信 organization: 金沢医科大学医学部形成外科 – sequence: 1 fullname: 赤井, 卓也 organization: 富山大学医学部脳神経外科 – sequence: 1 fullname: 飯塚, 秀明 organization: 金沢医科大学医学部脳神経外科 – sequence: 1 fullname: 黒田, 敏 organization: 富山大学医学部脳神経外科 |
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| Copyright | 2019 日本脳神経外科コングレス |
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| DOI | 10.7887/jcns.28.197 |
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| References | 10) Cornelissen MJ, Loudon SE, van Doorn FE, Muller RP, van Veelen MC, Mathijssen IM : Very Low Prevalence of Intracranial Hypertension in Trigonocephaly. Plast Reconstr Surg 139 : 97e-104e, 2017. 25) Mathijssen I, Arnaud E, Lajeunie E, Marchac D, Renier D : Postoperative cognitive outcome for synostotic frontal plagiocephaly. J Neurosurg 105 (1 Suppl) : 16-20, 2006. 23) Kosty J, Vogel TW : Insights into the development of molecular therapies for craniosynostosis. Neurosurg Focus 38 : E2, 2015. 6) Chieffo D, Tamburrini G, Massimi L, Di Giovanni S, Giansanti C, Caldarelli M, Di Rocco C : Long-term neuropsychological development in single-suture craniosynostosis treated early. J Neoursurg Pediatr 5 : 232-237, 2010. 14) Hirabayashi S, Sugawara Y, Sakurai A, Harii K, Park S : Frontoorbital advancement by gradual distraction. Technical note. J Neurosurg 89 : 1058-1061, 1998. 36) Shimoji T, Kimura T, Shimoji K, Miyajima M : The metopic-sagittal craniosynostosis―report of 35 operative cases. Childs Nerv Syst 33 : 1335-1348, 2017. 39) Starr JR, Kapp-Simon KA, Cloonan YK, Collett BR, Cradock MM, Buono L, Cunningham ML, Speltz ML : Presurgical and postsurgical assessment of the neurodevelopment of infants with single-suture craniosynostosis : comparison with controls. J Neurosurg 107 (2 Supple) : 103-110, 2007. 24) Lattanzi W, Barba M, Di Pietro L, Boyadjiev SA : Genetic advances in craniosynostosis. Am J Med Genet A 173 : 1406-1429, 2017. 19) Jimenez DF, Barone CM : Endoscopic technique for coronal synostosis. Childs Nerv Syst 28 : 1429-1432, 2012. 37) Shukla V, Coumoul X, Wang RH, Kim HS, Deng CX : RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis. Nat Genet 39 : 1145-1150, 2007. 17) Jimenez DF, Barone CM : Endoscopic craniectomy for early surgical correction of sagittal craniosynostosis. J Neurosurg 88 : 77-81, 1998. 22) Komatsu Y, Yu PB, Kamiya N, Pan H, Fukuda T, Scott GJ, Ray MK, Yamamura K, Mishina Y : Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice. J Bone Miner Res 28 : 1422-1433, 2013. 20) Jimenez DF, Barone CM : Early treatment of coronal synostosis with endoscopy-assisted craniectomy and postoperative cranial orthosis therapy : 16-year experience. J Neurosurg Pediatr 12 : 207-219, 2013. 8) Cohen SR, Persing JA : Intracranial pressure in single-suture craniosynostosis. Cleft Palate Craniofac J 35 : 194-196, 1998. 15) Ijichi S, Ijichi N, Ishida A, Yotsumoto M, Nagata J, Tanuma R, Imamura C, Toki A, Sakajiri T, Hirotsune H, Nakadoi Y, Tanaka S, Kimura K, Tanaka K : Ethical fallacies, tricky ambiguities, and the misinterpretation of the outcomes in the cranioplasty for mild trigonocephaly. Childs Nerv Syst 31 : 1009-1012, 2015. 46) Yokota M, Kobayashi Y, Morita J, Suzuki H, Hashimoto Y, Sasaki Y, Akiyoshi K, Moriyama K : Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. PLoS One 9 : e101693, 2014. 21) Jimenez DF, McGinity MJ, Barone CM : Endoscopy-assisted early correction of single-suture metopic craniosynostosis : a 19-year experience. J Neurosurg Pediatr : 1-14, 2018. [Epub ahead of print] 43) Takahashi Y, Hori M, Shimoji K, Miyajima M, Akiyama O, Arai H, Aoki S : Changes in delta ADC reflect intracranial pressure changes in craniosynostosis. Acta Radiol Open 6 : 2058460117728535. doi : 10.1177/2058460117728535. eCollection 2017. 44) Tessier P : Relationship of craniosynostosis to craniofacial dysostosis and to faciostenosis : a study with therapeutic implications. Plast Reconstr Surg 48 : 224-237, 1971. 1) Akai T, Iizuka H, Kishibe M, Kawakami S, Kobayashi A, Ozawa T : A case of Beare-Stevenson cutis gyrata syndrome confirmed by mutation analysis of the fibroblast growth factor receptor 2 gene. Pediatr Neurosurg 37 : 97-99, 2002. 5) Bonfield CM, Foley LM, Kundu S, Fellows-Mayle W, Hitchens TK, Rohde GK, Grandhi R, Mooney MP : The influence of surgical correction on white matter microstructural integrity in rabbits with familial coronal suture craniosynostosis. Neurosurg Focus 38 : E3, 2015. 32) Roscioli T, Elakis G, Cox TC, Moon DJ, Venselaar H, Turner AM, Le T, Hackett E, Haan E, Colley A, Mowat D, Worgan L, Kirk EP, Sachdev R, Thompson E, Gabbett M, McGaughran J, Gibson K, Gattas M, Freckmann ML, Dixon J, Hoefsloot L, Field M, Hackett A, Kamien B, Edwards M, Adès LC, Collins FA, Wilson MJ, Savarirayan R, Tan TY, Amor DJ, McGillivray G, White SM, Glass IA, David DJ, Anderson PJ, Gianoutsos M, Buckley MF : Genotype and clinical care correlations in craniosynostosis : findings from a cohort of 630 Australian and New Zealand patients. Am J Med Genet C Semin Med Genet 163C : 259-70, 2013. 31) Renier D, Lajeunie E, Arnaud E, Marchac D : Management of craniosynostosis. Childs Nerv Syst 16 : 645-658, 2000. 41) Sugawara Y, Hirabayashi S, Sakurai A, Harii K : Gradual cranial vault expansion for the treatment of craniofacial synostosis : a preliminary report. Ann Plast Surg 40 : 544-565, 1998. 40) Starr JR, Collett BR, Gaither R, Kapp-Simon KA, Cradock MM, Cunningham ML, Speltz ML : Multicenter study of neurodevelopment in 3-year-old children with and without single-suture craniosynostosis. Arch Pediatr Adolesc Med 166 : 536-542, 2012. 47) Wagner JD, Cohen SR, Maher H, Dauser RC, Newman MH : Critical analysis of results of craniofacial surgery for nonsyndromic bicoronal synostosis. J Craniofac Surg 6 : 32-37, 1995. 9) Collett BR, Kapp-Simon KA, Wallace E, Cradock MM, Buono L, Speltz ML : Attention and executive function in children with and without single-suture craniosynostosis. Child Neuropsychol 23 : 83-98, 2017. 34) Salokorpi N, Vuollo V, Sinikumpu JJ, Satanin L, Nestal Zibo H, Ylikontiola LP, Pirttiniemi P, Sándor GK, Serlo W : Increases in cranial volume with posterior cranial vault distraction in 31 consecutive cases. Neurosurgery 81 : 803-811, 2017. 26) McCarthy JG, Schreiber J, Karp N, Thorne CH, Grayson BH : Lengthening the human mandible by gradual distraction. Plast Reconstr Surg 89 : 1-8, 1992. 30) Osawa T, Mase M, Miyati T, Kan H, Demura K, Kasai H, Hara M, Shibamoto Y, Yamada K : Delta-ADC (apparent diffusion coefficient) analysis in patients with idiopathic normal pressure hydrocephalus. Acta Neurochir Suppl 114 : 197-200, 2012. 35) Shimoji T, Tominaga D, Shimoji K, Miyajima M, Tasato K : Analysis of pre- and post-operative symptoms of patients with mild trigonocephaly using several developmental and psychological tests. Childs Nerv Syst 31 : 433-440, 2015. 45) Twigg SR, Wilkie AO : A Genetic-Pathophysiological Framework for Craniosynostosis. Am J Hum Genet 97 : 359-377, 2015. 38) Spruijt B, Rijken BF, den Ottelander BK, Joosten KF, Lequin MH, Loudon SE, van Veelen ML, Mathijssen IM : First vault expansion in Apert and Crouzon-Pfeiffer syndromes : Front or back? Plastr Reconstr Surg 137 : 112e-121e, 2016. 27) Mooney MP, Losken HW, Moursi AM, Bradley J, Azari K, Acarturk TO, Cooper GM, Thompson B, Opperman LA, Siegel MI : Anti-TGF-beta2 antibody therapy inhibits postoperative resynostosis in craniosynostotic rabbits. Plast Reconstr Surg 119 : 1200-1212, 2007. 4) Bellew M, Chumas P, Mueller R, Liddington M, Russell J : Pre- and postoperative developmental attainment in sagittal synostosis. Arch Dis Child 90 : 346-350, 2005. 11) Dalle Ore CL, Dilip M, Brandel MG, Mclntyre JK, Hoshide R, Calayag M, Gosman AA, Cohen SR, Meltzer HS : Endoscopic surgery for nonsyndromic craniosynostosis : a 16-year single-center experience. J Neurosurg Pediatr 22 : 335-343, 2018. 33) Ruane EJ, Garland CB, Camison L, Fenton RA, Nischal KK, Pollack IF, Tamber MS, Grunwaldt LJ, Losee JE, Goldstein JA : A Treatment Algorithm for Patients Presenting with Sagittal Craniosynostosis after the Age of 1 Year. Plast Reconstr Surg 140 : 582-590, 2017. 29) Nguyen DC, Farber SJ, Skolnick GB, Naidoo SD, Smyth MD, Kane AA, Patel KB, Woo AS : One hundred consecutive endoscopic repairs of sagittal craniosynostosis : an elevation in care. J Neurosurg Pediatr 20 : 410-418, 2017. 12) Frazier BC, Mooney MP, Losken HW, Barbano T, Moursi A, Siegel MI, Richtsmeier JT : Comparison of craniofacial phenotype in craniosynostotic rabbits treated with anti-Tgf-beta2 at suturectomy site. Cleft Palate Craniofac J 45 : 571-582, 2008. 42) 菅原康志, 辻 直子, 須永 中, 野村紘史, 香川広司, 宇田宏一, 去川俊二, 平林慎一 : Multi-directional cranial distraction osteogenesis (MCDO) システムによる頭蓋縫合早期癒合症の治療. 形成外科 48 : 1017-1025, 2005. 48) Wilkie AO, Bochukova EG, Hansen RM, Taylor IB, Rannan-Eliya SV, Byren JC, Wall SA, Ramos L, Venâncio M, Hurst JA, O’rourke AW, Williams LJ, Seller A, Lester T : Clinical dividends from the molecular genetic diagnosis of craniosynostosis. Am J Med Genet A 143 A : 1941-1949, 2007. 7) Chummun S, McLean NR, Flapper WJ, David DJ : The Management of Nonsyndromic, Isolated Sagittal Synostosis. J Craniofac Surg 27 : 299-304, 2016. 13) Hicdonmez T : Children with Metopic Ridge. Turk Neurosurg 27 : 585-589, 2017. 16) Ijichi S, Ijichi N, Sameshima H, Kawaike Y, Imamura C, Hazama K, Hirotsune H, Kimura K, Nakadoi Y, Oiji A, Ota J, Sakajiri T, Tanaka S, Tanaka K : A concise checklist to determine if the congnitive and/or behavioral changes are attributable to the effect of an intervention. Childs Nerv Syst 33 : 1429-1432, 2017. 28) Mooney MP, Losken HW, Moursi AM, Shand JM, Cooper GM, Curry C, Ho L, Burrows AM, Stelnicki EJ, Losee JE, Opperman LA, Siegel MI : Postoperative anti-Tgf-beta2 antibody therapy improves intracranial volume and craniofacial growth in craniosynostotic rabbits. J Craniofac Surg 18 : 336-346, 2007. 2) Akai T, Iizuka H, Kawakami S : Treatment of craniosynostosis by distraction osteogenesis. Pediatr Neurosurg 42 : 288-292, 2006. 3) Arnaud E, Meneses P, Lajeunie E, Thorne JA, Marchac D, Renier D : Postoperative mental and morphological outcome for nonsyndromic brachycephaly. Plast Reconstr Surg 110 : 6-12, 2002. 18) Jimenez DF, Barone CM, Cartwright CC, Baker L : Early management of craniosynostosis using endoscopic-assisted stri |
| References_xml | – reference: 25) Mathijssen I, Arnaud E, Lajeunie E, Marchac D, Renier D : Postoperative cognitive outcome for synostotic frontal plagiocephaly. J Neurosurg 105 (1 Suppl) : 16-20, 2006. – reference: 14) Hirabayashi S, Sugawara Y, Sakurai A, Harii K, Park S : Frontoorbital advancement by gradual distraction. Technical note. J Neurosurg 89 : 1058-1061, 1998. – reference: 29) Nguyen DC, Farber SJ, Skolnick GB, Naidoo SD, Smyth MD, Kane AA, Patel KB, Woo AS : One hundred consecutive endoscopic repairs of sagittal craniosynostosis : an elevation in care. J Neurosurg Pediatr 20 : 410-418, 2017. – reference: 37) Shukla V, Coumoul X, Wang RH, Kim HS, Deng CX : RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis. Nat Genet 39 : 1145-1150, 2007. – reference: 43) Takahashi Y, Hori M, Shimoji K, Miyajima M, Akiyama O, Arai H, Aoki S : Changes in delta ADC reflect intracranial pressure changes in craniosynostosis. Acta Radiol Open 6 : 2058460117728535. doi : 10.1177/2058460117728535. eCollection 2017. – reference: 23) Kosty J, Vogel TW : Insights into the development of molecular therapies for craniosynostosis. Neurosurg Focus 38 : E2, 2015. – reference: 27) Mooney MP, Losken HW, Moursi AM, Bradley J, Azari K, Acarturk TO, Cooper GM, Thompson B, Opperman LA, Siegel MI : Anti-TGF-beta2 antibody therapy inhibits postoperative resynostosis in craniosynostotic rabbits. Plast Reconstr Surg 119 : 1200-1212, 2007. – reference: 13) Hicdonmez T : Children with Metopic Ridge. Turk Neurosurg 27 : 585-589, 2017. – reference: 9) Collett BR, Kapp-Simon KA, Wallace E, Cradock MM, Buono L, Speltz ML : Attention and executive function in children with and without single-suture craniosynostosis. Child Neuropsychol 23 : 83-98, 2017. – reference: 3) Arnaud E, Meneses P, Lajeunie E, Thorne JA, Marchac D, Renier D : Postoperative mental and morphological outcome for nonsyndromic brachycephaly. Plast Reconstr Surg 110 : 6-12, 2002. – reference: 48) Wilkie AO, Bochukova EG, Hansen RM, Taylor IB, Rannan-Eliya SV, Byren JC, Wall SA, Ramos L, Venâncio M, Hurst JA, O’rourke AW, Williams LJ, Seller A, Lester T : Clinical dividends from the molecular genetic diagnosis of craniosynostosis. Am J Med Genet A 143 A : 1941-1949, 2007. – reference: 21) Jimenez DF, McGinity MJ, Barone CM : Endoscopy-assisted early correction of single-suture metopic craniosynostosis : a 19-year experience. J Neurosurg Pediatr : 1-14, 2018. [Epub ahead of print] – reference: 34) Salokorpi N, Vuollo V, Sinikumpu JJ, Satanin L, Nestal Zibo H, Ylikontiola LP, Pirttiniemi P, Sándor GK, Serlo W : Increases in cranial volume with posterior cranial vault distraction in 31 consecutive cases. Neurosurgery 81 : 803-811, 2017. – reference: 16) Ijichi S, Ijichi N, Sameshima H, Kawaike Y, Imamura C, Hazama K, Hirotsune H, Kimura K, Nakadoi Y, Oiji A, Ota J, Sakajiri T, Tanaka S, Tanaka K : A concise checklist to determine if the congnitive and/or behavioral changes are attributable to the effect of an intervention. Childs Nerv Syst 33 : 1429-1432, 2017. – reference: 28) Mooney MP, Losken HW, Moursi AM, Shand JM, Cooper GM, Curry C, Ho L, Burrows AM, Stelnicki EJ, Losee JE, Opperman LA, Siegel MI : Postoperative anti-Tgf-beta2 antibody therapy improves intracranial volume and craniofacial growth in craniosynostotic rabbits. J Craniofac Surg 18 : 336-346, 2007. – reference: 41) Sugawara Y, Hirabayashi S, Sakurai A, Harii K : Gradual cranial vault expansion for the treatment of craniofacial synostosis : a preliminary report. Ann Plast Surg 40 : 544-565, 1998. – reference: 6) Chieffo D, Tamburrini G, Massimi L, Di Giovanni S, Giansanti C, Caldarelli M, Di Rocco C : Long-term neuropsychological development in single-suture craniosynostosis treated early. J Neoursurg Pediatr 5 : 232-237, 2010. – reference: 32) Roscioli T, Elakis G, Cox TC, Moon DJ, Venselaar H, Turner AM, Le T, Hackett E, Haan E, Colley A, Mowat D, Worgan L, Kirk EP, Sachdev R, Thompson E, Gabbett M, McGaughran J, Gibson K, Gattas M, Freckmann ML, Dixon J, Hoefsloot L, Field M, Hackett A, Kamien B, Edwards M, Adès LC, Collins FA, Wilson MJ, Savarirayan R, Tan TY, Amor DJ, McGillivray G, White SM, Glass IA, David DJ, Anderson PJ, Gianoutsos M, Buckley MF : Genotype and clinical care correlations in craniosynostosis : findings from a cohort of 630 Australian and New Zealand patients. Am J Med Genet C Semin Med Genet 163C : 259-70, 2013. – reference: 4) Bellew M, Chumas P, Mueller R, Liddington M, Russell J : Pre- and postoperative developmental attainment in sagittal synostosis. Arch Dis Child 90 : 346-350, 2005. – reference: 42) 菅原康志, 辻 直子, 須永 中, 野村紘史, 香川広司, 宇田宏一, 去川俊二, 平林慎一 : Multi-directional cranial distraction osteogenesis (MCDO) システムによる頭蓋縫合早期癒合症の治療. 形成外科 48 : 1017-1025, 2005. – reference: 44) Tessier P : Relationship of craniosynostosis to craniofacial dysostosis and to faciostenosis : a study with therapeutic implications. Plast Reconstr Surg 48 : 224-237, 1971. – reference: 46) Yokota M, Kobayashi Y, Morita J, Suzuki H, Hashimoto Y, Sasaki Y, Akiyoshi K, Moriyama K : Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. PLoS One 9 : e101693, 2014. – reference: 20) Jimenez DF, Barone CM : Early treatment of coronal synostosis with endoscopy-assisted craniectomy and postoperative cranial orthosis therapy : 16-year experience. J Neurosurg Pediatr 12 : 207-219, 2013. – reference: 31) Renier D, Lajeunie E, Arnaud E, Marchac D : Management of craniosynostosis. Childs Nerv Syst 16 : 645-658, 2000. – reference: 45) Twigg SR, Wilkie AO : A Genetic-Pathophysiological Framework for Craniosynostosis. Am J Hum Genet 97 : 359-377, 2015. – reference: 38) Spruijt B, Rijken BF, den Ottelander BK, Joosten KF, Lequin MH, Loudon SE, van Veelen ML, Mathijssen IM : First vault expansion in Apert and Crouzon-Pfeiffer syndromes : Front or back? Plastr Reconstr Surg 137 : 112e-121e, 2016. – reference: 2) Akai T, Iizuka H, Kawakami S : Treatment of craniosynostosis by distraction osteogenesis. Pediatr Neurosurg 42 : 288-292, 2006. – reference: 33) Ruane EJ, Garland CB, Camison L, Fenton RA, Nischal KK, Pollack IF, Tamber MS, Grunwaldt LJ, Losee JE, Goldstein JA : A Treatment Algorithm for Patients Presenting with Sagittal Craniosynostosis after the Age of 1 Year. Plast Reconstr Surg 140 : 582-590, 2017. – reference: 19) Jimenez DF, Barone CM : Endoscopic technique for coronal synostosis. Childs Nerv Syst 28 : 1429-1432, 2012. – reference: 8) Cohen SR, Persing JA : Intracranial pressure in single-suture craniosynostosis. Cleft Palate Craniofac J 35 : 194-196, 1998. – reference: 12) Frazier BC, Mooney MP, Losken HW, Barbano T, Moursi A, Siegel MI, Richtsmeier JT : Comparison of craniofacial phenotype in craniosynostotic rabbits treated with anti-Tgf-beta2 at suturectomy site. Cleft Palate Craniofac J 45 : 571-582, 2008. – reference: 35) Shimoji T, Tominaga D, Shimoji K, Miyajima M, Tasato K : Analysis of pre- and post-operative symptoms of patients with mild trigonocephaly using several developmental and psychological tests. Childs Nerv Syst 31 : 433-440, 2015. – reference: 40) Starr JR, Collett BR, Gaither R, Kapp-Simon KA, Cradock MM, Cunningham ML, Speltz ML : Multicenter study of neurodevelopment in 3-year-old children with and without single-suture craniosynostosis. Arch Pediatr Adolesc Med 166 : 536-542, 2012. – reference: 11) Dalle Ore CL, Dilip M, Brandel MG, Mclntyre JK, Hoshide R, Calayag M, Gosman AA, Cohen SR, Meltzer HS : Endoscopic surgery for nonsyndromic craniosynostosis : a 16-year single-center experience. J Neurosurg Pediatr 22 : 335-343, 2018. – reference: 17) Jimenez DF, Barone CM : Endoscopic craniectomy for early surgical correction of sagittal craniosynostosis. J Neurosurg 88 : 77-81, 1998. – reference: 15) Ijichi S, Ijichi N, Ishida A, Yotsumoto M, Nagata J, Tanuma R, Imamura C, Toki A, Sakajiri T, Hirotsune H, Nakadoi Y, Tanaka S, Kimura K, Tanaka K : Ethical fallacies, tricky ambiguities, and the misinterpretation of the outcomes in the cranioplasty for mild trigonocephaly. Childs Nerv Syst 31 : 1009-1012, 2015. – reference: 5) Bonfield CM, Foley LM, Kundu S, Fellows-Mayle W, Hitchens TK, Rohde GK, Grandhi R, Mooney MP : The influence of surgical correction on white matter microstructural integrity in rabbits with familial coronal suture craniosynostosis. Neurosurg Focus 38 : E3, 2015. – reference: 7) Chummun S, McLean NR, Flapper WJ, David DJ : The Management of Nonsyndromic, Isolated Sagittal Synostosis. J Craniofac Surg 27 : 299-304, 2016. – reference: 26) McCarthy JG, Schreiber J, Karp N, Thorne CH, Grayson BH : Lengthening the human mandible by gradual distraction. Plast Reconstr Surg 89 : 1-8, 1992. – reference: 10) Cornelissen MJ, Loudon SE, van Doorn FE, Muller RP, van Veelen MC, Mathijssen IM : Very Low Prevalence of Intracranial Hypertension in Trigonocephaly. Plast Reconstr Surg 139 : 97e-104e, 2017. – reference: 47) Wagner JD, Cohen SR, Maher H, Dauser RC, Newman MH : Critical analysis of results of craniofacial surgery for nonsyndromic bicoronal synostosis. J Craniofac Surg 6 : 32-37, 1995. – reference: 30) Osawa T, Mase M, Miyati T, Kan H, Demura K, Kasai H, Hara M, Shibamoto Y, Yamada K : Delta-ADC (apparent diffusion coefficient) analysis in patients with idiopathic normal pressure hydrocephalus. Acta Neurochir Suppl 114 : 197-200, 2012. – reference: 22) Komatsu Y, Yu PB, Kamiya N, Pan H, Fukuda T, Scott GJ, Ray MK, Yamamura K, Mishina Y : Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice. J Bone Miner Res 28 : 1422-1433, 2013. – reference: 39) Starr JR, Kapp-Simon KA, Cloonan YK, Collett BR, Cradock MM, Buono L, Cunningham ML, Speltz ML : Presurgical and postsurgical assessment of the neurodevelopment of infants with single-suture craniosynostosis : comparison with controls. J Neurosurg 107 (2 Supple) : 103-110, 2007. – reference: 1) Akai T, Iizuka H, Kishibe M, Kawakami S, Kobayashi A, Ozawa T : A case of Beare-Stevenson cutis gyrata syndrome confirmed by mutation analysis of the fibroblast growth factor receptor 2 gene. Pediatr Neurosurg 37 : 97-99, 2002. – reference: 18) Jimenez DF, Barone CM, Cartwright CC, Baker L : Early management of craniosynostosis using endoscopic-assisted strip craniectomies and cranial orthotic molding therapy. Pediatrics 110 (1 Pt 1) : 97-104, 2002. – reference: 24) Lattanzi W, Barba M, Di Pietro L, Boyadjiev SA : Genetic advances in craniosynostosis. Am J Med Genet A 173 : 1406-1429, 2017. – reference: 36) Shimoji T, Kimura T, Shimoji K, Miyajima M : The metopic-sagittal craniosynostosis―report of 35 operative cases. Childs Nerv Syst 33 : 1335-1348, 2017. |
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| SubjectTerms | craniosynostosis diagnosis treatment |
| Title | 頭蓋骨縫合早期癒合症の診断と治療―現状と課題 |
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