閉塞性動脈硬化症における近赤外線分光法の回復時間と心血管予後との関連性

要 旨:閉塞性動脈硬化症の患者に対し,近赤外線分光法(NIRS)にて測定された運動負荷試験後の下肢虚血の回復時間(RT)と,心血管予後との関連性を検討した。観察期間は9.2±2.1年であった。心血管イベント発症群と発症しなかった群とで比較すると,患者の両下肢のうち回復が遅かったほうの肢のRTは,有意差はなかったもののイベント発症群で長かった。NIRSで測定されたRTは,心血管予後に関連する可能性がある。...

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Published in脈管学 Vol. 52; no. February; pp. 123 - 127
Main Authors 高江, 久仁, 佐伯, 直純, 重松, 宏, 小泉, 信達, 渡部, 芳子, 小櫃, 由樹生
Format Journal Article
LanguageJapanese
Published 日本脈管学会 10.02.2012
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ISSN0387-1126
1880-8840
DOI10.7133/jca.52.123

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Abstract 要 旨:閉塞性動脈硬化症の患者に対し,近赤外線分光法(NIRS)にて測定された運動負荷試験後の下肢虚血の回復時間(RT)と,心血管予後との関連性を検討した。観察期間は9.2±2.1年であった。心血管イベント発症群と発症しなかった群とで比較すると,患者の両下肢のうち回復が遅かったほうの肢のRTは,有意差はなかったもののイベント発症群で長かった。NIRSで測定されたRTは,心血管予後に関連する可能性がある。
AbstractList 要 旨:閉塞性動脈硬化症の患者に対し,近赤外線分光法(NIRS)にて測定された運動負荷試験後の下肢虚血の回復時間(RT)と,心血管予後との関連性を検討した。観察期間は9.2±2.1年であった。心血管イベント発症群と発症しなかった群とで比較すると,患者の両下肢のうち回復が遅かったほうの肢のRTは,有意差はなかったもののイベント発症群で長かった。NIRSで測定されたRTは,心血管予後に関連する可能性がある。
Author 小泉, 信達
小櫃, 由樹生
佐伯, 直純
渡部, 芳子
高江, 久仁
重松, 宏
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  fullname: 佐伯, 直純
  organization: 東京医科大学外科学第2講座(血管外科)
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  fullname: 重松, 宏
  organization: 山王メディカルセンター血管病センター,国際医療福祉大学
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  fullname: 渡部, 芳子
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  fullname: 小櫃, 由樹生
  organization: 国際医療福祉大学三田病院血管外科
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References 3)Leng GC, Lee AJ, Fowkes FG, et al: Incidence, natural history and cardiovascular events in symptomatic and asymptomatic peripheral arterial disease in the general population. Int J Epidemiol 1996; 25: 1172-1181
9)Studenski S, Perera S, Patel K, et al: Gait speed and survival in older adults. JAMA 2011; 305: 50-58
5)Delp MD, Laughlin MH: Regulation of skeletal muscle perfusion during exercise. Acta Physiol Scand 1998; 162: 411-419
2)Fowkes FG, Housley E, Cawood EH, et al: Edinburgh Artery Study: prevalence of asymptomatic and symptomatic peripheral arterial disease in the general population. Int J Epidemiol 1991; 20: 384-392
4)Mehler PS, Coll JR, Estacio R, et al: Intensive blood pressure control reduces the risk of cardiovascular events in patients with peripheral arterial disease and type 2 diabetes. Circulation 2003; 107: 753-756
6)市来正隆:近赤外線分光法による肢機能評価の意義間歇性跛行肢に対する機能的評価と近赤外線分光法を利用した効率的な歩行運動療法.脈管学 2010; 50: 449-454
8)Mohler ER, Lech G, Supple GE, et al: Impaired exercise-induced blood volume in type 2 diabetes with or without peripheral arterial disease measured by continuous-wave near-infrared spectroscopy. Diabetes Care 2006; 29: 1856-1859
1)Hirsch AT, Haskal ZJ, Hertzer NR, et al: ACC/AHA 2005 Practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): Executive summary-A collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA task force on practice guidelines (Writing committee to develop guidelines for the management of patients with peripheral arterial disease). Circulation 2006; 113: 1474-1547
7)Kime R, Im J, Moser D, et al: Noninvasive determination of exercise-induced vasodilation during bicycle exercise using near infrared spectroscopy. Med Sci Monit 2009; 15: CR89-CR94
References_xml – reference: 1)Hirsch AT, Haskal ZJ, Hertzer NR, et al: ACC/AHA 2005 Practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): Executive summary-A collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA task force on practice guidelines (Writing committee to develop guidelines for the management of patients with peripheral arterial disease). Circulation 2006; 113: 1474-1547
– reference: 9)Studenski S, Perera S, Patel K, et al: Gait speed and survival in older adults. JAMA 2011; 305: 50-58
– reference: 3)Leng GC, Lee AJ, Fowkes FG, et al: Incidence, natural history and cardiovascular events in symptomatic and asymptomatic peripheral arterial disease in the general population. Int J Epidemiol 1996; 25: 1172-1181
– reference: 4)Mehler PS, Coll JR, Estacio R, et al: Intensive blood pressure control reduces the risk of cardiovascular events in patients with peripheral arterial disease and type 2 diabetes. Circulation 2003; 107: 753-756
– reference: 6)市来正隆:近赤外線分光法による肢機能評価の意義間歇性跛行肢に対する機能的評価と近赤外線分光法を利用した効率的な歩行運動療法.脈管学 2010; 50: 449-454
– reference: 7)Kime R, Im J, Moser D, et al: Noninvasive determination of exercise-induced vasodilation during bicycle exercise using near infrared spectroscopy. Med Sci Monit 2009; 15: CR89-CR94
– reference: 8)Mohler ER, Lech G, Supple GE, et al: Impaired exercise-induced blood volume in type 2 diabetes with or without peripheral arterial disease measured by continuous-wave near-infrared spectroscopy. Diabetes Care 2006; 29: 1856-1859
– reference: 2)Fowkes FG, Housley E, Cawood EH, et al: Edinburgh Artery Study: prevalence of asymptomatic and symptomatic peripheral arterial disease in the general population. Int J Epidemiol 1991; 20: 384-392
– reference: 5)Delp MD, Laughlin MH: Regulation of skeletal muscle perfusion during exercise. Acta Physiol Scand 1998; 162: 411-419
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Snippet 要 旨:閉塞性動脈硬化症の患者に対し,近赤外線分光法(NIRS)にて測定された運動負荷試験後の下肢虚血の回復時間(RT)と,心血管予後との関連性を検討した。観察期...
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StartPage 123
SubjectTerms atherothrombosis
cardiovascular disease
near-infrared spectroscopy
peripheral artery disease
prognosis
Title 閉塞性動脈硬化症における近赤外線分光法の回復時間と心血管予後との関連性
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