Pilocytic astrocytoma 再発の１例

• Published in: Neuro-Oncologyの進歩 Vol. 24; no. 1; pp. 22 - 26
• Main Authors: 吉村, 晋一, 亀井, 孝昌, 岩田, 亮一, 大石, 哲也, 李, 一, 二宮, 英樹, 染野, 裕美子, 埜中, 正博, 武田, 純一, 大重, 英行, 淺井, 昭雄
• Format: Journal Article
• Language: English
• Published: 近畿脳腫瘍病理検討会 2017; Kinki Brain Tumor Pathology Conference
• Subjects: pilocytic astrocytoma; recurrence
• ISSN: 1880-0742; 2187-0551
• DOI: 10.11452/neurooncology.24.1_22

Pilocytic astrocytoma (PA) is the brain tumor frequently found in children. Surgery is curative therapy in areas of the brain amenable to complete resection. However, the tumor located in areas where complete resection is not possible can threaten both function and life. The appropriate treatment is unclear yet. Options include chemotherapy, radiation therapy, surgical resection or a combination. The authors present the case of a 7-year-old girl with right arm paralysis and a biopsy-proven pilocytic astrocytoma in the left basal ganglia.Chemotherapy was performed after biopsy and disappearance of the enhanced area was confirmed. MRI examination revealed that tumor recurrence six months after chemotherapy, so a total extirpation was performed. The pathological findings showed no degenerative change and the MIB-1 index was 4-7%. No post operation therapy was performed.