THE EFFECTS OF EXERCISE ON HEMODYNAMICS AND PULMONARY GAS EXCHANGE IN PATIENTS WITH CHRONIC PULMONARY DISEASE

• Published in: Japanese Journal of National Medical Services Vol. 44; no. 10; pp. 978 - 984
• Main Authors: YOSHIMURA, Rikiya, SUGIURA, Tatsutaka, IKEJIRI, Koji, MOROTOMI, Kunio, YOSHIDA, Yasuhiro, AKAHOSHI, Ryuichiro
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1990; 一般社団法人 国立医療学会
• Subjects: chronic pulmonary disease; exercise; hemodynamics; pulmonary gas exchange; 慢性肺疾患; 血液ガス; 血行動態; 運動負荷
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.44.978

The changes of hemodynamics and pulmonary gas exchange at rest and on exercise were studied in 15 patients with chronic pulmonary disease. The following results were obtained. 1) Patients who developed exertional hypoxemia (group B) had a higher resting heart rate and a lower %VC than patients who did not (group A). 2) Heart rate was positively correlated with mean pulmonary arterial pressure (PPA) and cardiac output, but inversely correlated with arterial oxygen tension (PaO2) and oxygen saturation (SaO2) both at rest and on exercise. 3) %VC was positively correlated with PaO2, but inversely correlated with heart rate and PPA both at rest and on exercise. 4) Right ventricular e-jection fraction at rest remained well preserved in our patients of both groups. However, occult right ventricular dysfunction became apparent in group B on exercise, as compared to group A.