Influence of age and coronary risk factors on standard 12 lead electrocardiogram

• Published in: Journal of the Japanese Association for Cerebro-cardiovascular Disease Control Vol. 27; no. 2; pp. 94 - 99
• Main Authors: Suzuki, Shinichiro, Asai, Ryuji, Yoshida, Masanori, Tamura, Shizuo, Yagi, Hiroshi, Hosogai, Hiroaki
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Association for Cerebro-cardiovascular Disease Control 1992; 社団法人 日本循環器管理研究協議会
• Subjects: aging; coronary risk factors; electrocardiogram; 冠危険因子; 加齢; 標準12誘導心電図
• ISSN: 0914-7284
• DOI: 10.11381/jjcdp1974.27.94

In order to determine whether age and coronary risk factors influence standard 12 lead ECG variables, 8966 male and 1618 female NTT workers, aged 20 to 59 years who underwent health examination at NTT Tokyo health administration center from April to September in 1990, were studied. These workers were divided into two groups as follows : (1) General subjects consistng of 1112 males and 716 females aged 20 to 59 years who were selected randomly out of the 8966 males and 1618 females. (2) Control subjects consisting of 1019 males and 81 females aged 30 to 59 years without hypercholesteremia, diabetes melitis, obesity, hypertension, cigarette smoking, electroionic abnormalities and systemic disorder. In an earlier study (1989), we reported the significant prolongation of PQ interval, QRS duration and QTc width and QRS axis deviation to the left on frontal plane developed with age, but with no significant change in heart rate. In the present study similar results as a 1989 study were observed in general subjects. In control subjects, these significant changes of standard ECG variables except for QTc width in male were diminished in both sexes with age. These results indicate that coronary risk factors electroionic abnormalities and systemic disorders may be factors that determine changes in electrophysiological properties which were evaluated by standard 12 lead ECG seen in the process of aging.