A Study of the Effects of Left Ventricular Assist Device on Acute Myocardial Infarction

• Published in: Jinko Zoki Vol. 16; no. 1; pp. 63 - 66
• Main Authors: YUASA, H., TANAKA, K., IMURA, M., YADA, I., KUSAGAWA, M., MATSUOKA, M., WEI, C.M.
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1987; 一般社団法人 日本人工臓器学会
• Subjects: Coronary sinus blood flow; Left ventricular assist device; Myocardial blood flow; Myocardial oxygen consumption; Myocardial PO2, PCO2, pH
• ISSN: 0300-0818; 1883-6097
• DOI: 10.11392/jsao1972.16.63

The left heart bypass (LHB) experiments (Left atrium-aorta) were performed in failing hearts of twenty-three mongrel dogs using a centrifugal pump. Coronary sinus blood flow (CSBF), myocardial oxygen consumption (MOC), myocardial blood flow (MBF) and myocardial PO2, PCO2, pH were studied before and during LHB. During LHB, the MBF was effectively distributed to important regions of the damaged left ventricular (LV) through auto-regulation mechanism, and the myocardial PO2, PCO2, pH were significantly imporved. In conclusion the LHB is a very useful mechanical circulatory assistance to improve local myocardial metabolism during cardiogenic shock.