Prevention of Chemotherapy-Induced Alopecia by a Hair Grower, Tetaris

• Published in: The Japanese Journal of Pediatric Hematology Vol. 4; no. 5; pp. 490 - 494
• Main Authors: KINOSHITA, Akitoshi, MORI, Taijiro, KUROSAWA, Yoshihiro, NAKAZAWA, Shinpei, IKEDA, Inao, OSANO, Mitsuru
• Format: Journal Article
• Language: Japanese
• Published: THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY 1990; 特定非営利活動法人 日本小児血液・がん学会
• Subjects: テタリス; 抗癌剤; 脱毛
• ISSN: 0913-8706; 1884-4723
• DOI: 10.11412/jjph1987.4.490

In order to prevent chemotherapy-induced alopecia, a hair grower, Tetaris (Sankei Pharmaceutical Co., Tokyo) was applied to the scalp. Five girls (from 5 to 15 years old) with localized malignant tumors were selected for this study. Thirty grams of Tetaris was applied the day before administration of anti-neoplastic drugs, and thereafter 6 grams was applied every morning and evening for 3 days. In LSA2-L2 protocol for non-Hodgkin's lymphoma, a small amount of hair loss was observed. However, alopecia was hardly noticed in the treatments of osteogenic sarcoma including high-dose MTX, ADM, CPM and CDDP. In all 5 cases, Tetaris was effective and all the patients did not suffer from inconveniences in their lives. Though the prevention was successful even in the cases treated with Tetaris alone, we realized that the effect of Tetaris was reinforced by scalp cooling, and hair loss was considerably reduced. A synergestic mechanism between cooling and Tetaris can be expected.