The Accuracy of a Non-invasive Liver Fibrosis Evaluation Method, Shear Wave Elastography : A Retrospective Pilot Study

Objective: We aimed to evaluate the diagnostic accuracy of shear wave elastography( SWE) for the assessment of liver fibrosis in patients with liver disease. Methods: A total of 54 consecutive patients who underwent SWE measurement and liver biopsy were included. Receiver-operator characteristic (RO...

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Published inShimane Journal of Medical Science Vol. 34; no. 2; pp. 47 - 53
Main Authors Satoshi KOTANI, Shuichi SATO, Naruaki KOHGE, Kosuke TSUKANO, Sayaka OGAWA, Satoshi YAMANOUCHI, Ryusaku KUSUNOKI, Masahito AIMI, Yoichi MIYAOKA, Hirofumi FUJISHIRO, Tomohiko YAMAMOTO, Hideyuki OHNUMA
Format Journal Article
LanguageEnglish
Japanese
Published SHIMANE UNIVERSITY FACULTY OF MEDICINE 01.12.2017
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ISSN0386-5959

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Summary:Objective: We aimed to evaluate the diagnostic accuracy of shear wave elastography( SWE) for the assessment of liver fibrosis in patients with liver disease. Methods: A total of 54 consecutive patients who underwent SWE measurement and liver biopsy were included. Receiver-operator characteristic (ROC) curves were constructed to calculate the area under the ROC curve (AUC) for F0-2 versus F3-4 and F0-3 versus F4. Results: Fibrosis scores estimated by SWE were F0 for 9 cases, F1 for 18 cases, F2 for 11 cases, F3 for 9 cases, and F4 for 7 cases. AUCs for severe fibrosis (F3 and F4) and cirrhosis (F4) were 0.931 (P < 0.001) and 0.916 (P < 0.001), respectively. Shear wave velocity correlated significantly with liver fibrosis obtained by liver biopsy (r = 0.679, P < 0.001). Conclusion: SWE is a useful and non-invasive technology to estimate liver fibrosis in liver disease regardless of etiology.
ISSN:0386-5959