Long-term survival with locally advanced panceatic body carcinoma and paraaortic lymph node metastasis treated by the combination of surgery, chemotherapy, and radiation

• Published in: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 73; no. 6; pp. 1536 - 1541
• Main Authors: IZUMO, Wataru, HURUKAWA, Kenji, KOMATSU, Akio, SHIGEMATSU, Kyousuke, YAMAZAKI, Kieko, KATSURAGAWA, Hideo, HURUKAWA, Tatsuya
• Format: Journal Article
• Language: Japanese
• Published: Japan Surgical Association 2012
• Subjects: combined modality therapy; pancreatic carcinoma; paraaortic lymph node metastasis
• ISSN: 1345-2843; 1882-5133
• DOI: 10.3919/jjsa.73.1536

We report a rare case of long-term survival by a patient who had locally advanced pancreatic body carcinoma with paraaortic lymph node metastasis after combined treatment by surgery, chemotherapy, and radiation.A 48-year-old woman had a pancreatic body carcinoma (2 cm in diameter) with paraaortic lymph node metastasis (lymph node number 16b1 and 17b). She underwent distal pancreatectomy with splenectomy (R0 resection). Histopathological examination revealed tubular adenocarcinoma (T3 M1 Stage IVb). After surgery, she received gemcitabine, S-1, and radiation, and she survived for 44 months. This case demonstrates that the combination of surgery, chemotherapy, and radiotherapy can be effective for prolonging survival in patients with advanced pancreatic carcinoma and paraaortic lymph node metastasis.