Matrix Mechanotransduction underlies vascular remodeling

• Published in: Transactions of Japanese Society for Medical and Biological Engineering Vol. Annual59; no. Abstract; p. 231
• Main Author: Yamashiro, Yoshito
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society for Medical and Biological Engineering 2021; 公益社団法人 日本生体医工学会
• ISSN: 1347-443X; 1881-4379
• DOI: 10.11239/jsmbe.Annual59.231

Tissues and cells control their functions by recognizing (sensing) and responding to the mechanical environment. The state of mechanical equilibrium is called tensegrity (tension integrity), and the maintenance of tensegrity is essential for maintaining the homeostasis of biological tissues. Mechanobiology has been gaining attention as a field of study to elucidate the mechanical response and tensegrity of living organisms, but if we want to apply it in the future, we must not only understand the mechanism but also develop techniques to control the its mechanism. In this session, researchers who promote cutting-edge mechanobiology will present the latest topics focusing on vascular remodeling, multi-view imaging, epithelial barriers, myocardial regeneration, mathematical models based on dynamic fluctuation of force, and mechanosensory mechanisms.