Motion correction algorithms for pediatric spinal cord diffusion tensor imaging

The purpose of this investigation was to determine a reliable motion correction method for pediatric spinal cord diffusion tensor imaging (DTI) and show effects of motion correction on DTI parameters in normal subjects and patients with spinal cord injury (SCI). Images were corrected for motion usin...

Full description

Saved in:
Bibliographic Details
Published in2012 38th Annual Northeast Bioengineering Conference (NEBEC) pp. 79 - 80
Main Authors Middleton, D. M., Mohamed, F. B., Barakat, N., Hunter, L. N., Finsterbusch, J., Faro, S. H., Shah, P., Samdani, A., Mulcahey, M. J.
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.03.2012
Subjects
Cost function
Diffusion tensor imaging
Image quality
Observers
Reliability
Spinal cord
Online AccessGet full text
ISBN9781467311410
1467311413
ISSN2160-6986
DOI10.1109/NEBC.2012.6206971

Cover

More Information
Summary:The purpose of this investigation was to determine a reliable motion correction method for pediatric spinal cord diffusion tensor imaging (DTI) and show effects of motion correction on DTI parameters in normal subjects and patients with spinal cord injury (SCI). Images were corrected for motion using two types of transformation and three cost functions. Corrected images and transformations were examined quantitatively and qualitatively. FA and MD indices were calculated pre- and post-motion correction. Blinded evaluation of pre- and post-correction images showed significant improvement in corrected images (p<;0.0001). Statistically significant (p=0.02) decrease in FA (14-21%) was found in post correction images for SCI subjects, while normals showed minimal FA reduction (<;5%) and were not significant. Quantitative and qualitative analysis showed rigid scaled-least-squares registration to be effective and reliable.
ISBN:9781467311410
1467311413
ISSN:2160-6986
DOI:10.1109/NEBC.2012.6206971