Simulation Study on Blood Glucose Control in Diabetics

In this paper, some theoretical analysis of the control of blood glucose levels in diabetic individuals is undertaken using a simple mathematical model of the dynamics of glucose and insulin interaction in the blood system developed by Bergman et al. One is an open-loop control, which is based on th...

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Bibliographic Details
Published in2007 1st International Conference on Bioinformatics and Biomedical Engineering Vol. 1; pp. 1103 - 1106
Main Authors Li, Chengwei, Hu, Ruiqiang
Format Conference Proceeding Journal Article
LanguageEnglish
Published IEEE 2007
Subjects
Blood
Control system analysis
Diabetes
Insulation life
Insulin
Mathematical model
MATLAB
Open loop systems
Sugar
Three-term control
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ISBN9781424411207
1424411203
ISSN2151-7614
DOI10.1109/ICBBE.2007.285

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Summary:In this paper, some theoretical analysis of the control of blood glucose levels in diabetic individuals is undertaken using a simple mathematical model of the dynamics of glucose and insulin interaction in the blood system developed by Bergman et al. One is an open-loop control, which is based on the mathematical model of insulin curve. The other is a closed-loop control, which is using a classic PID controller. The aim of the control performance was assessed in terms of its ability to track a setpoint (70 mg/dl)form initial state of hyperglycemia, as well as in response to a meal disturbance. The MATLAB simulation is performed to manifest the theoretical analysis. The development reported in this paper are expected to simplify the insulin delivery mechanism, thereby enhancing the quality of life of the patient.
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ISBN:9781424411207
1424411203
ISSN:2151-7614
DOI:10.1109/ICBBE.2007.285