Widening Spectrum of a Reversible Splenial Lesion with Transiently Reduced Diffusion

• Published in: American Journal of Neuroradiology Vol. 27; no. 4; pp. 836 - 838
• Main Authors: Takanashi, J, Barkovich, A.J, Shiihara, T, Tada, H, Kawatani, M, Tsukahara, H, Kikuchi, M, Maeda, M
• Format: Journal Article
• Language: English
• Published: Oak Brook, IL Am Soc Neuroradiology 01.04.2006; American Society of Neuroradiology
• Subjects: Biological and medical sciences; Brain; Brain Diseases - pathology; Child; Child, Preschool; Corpus Callosum - pathology; Encephalitis - pathology; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging; Male; Medical sciences; Nervous system; Neurology; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Remission, Spontaneous; Retrospective Studies; Vascular diseases and vascular malformations of the nervous system; Radiodiagnosis; Diffusion; Nervous system diseases
• ISSN: 0195-6108; 1936-959X

Four patients with encephalitis/encephalopathy and parenchymal lesions accompanying reversible splenial lesions were retrospectively evaluated. In 3 patients, reversible lesions with transiently reduced diffusion were seen in the splenium and symmetrically in the peripheral frontoparietal white matter, clinical signs and symptoms were mild, and recovery was complete. These and previous observations suggest a less severe course and outcome for patients with reversible lesions isolated to the splenium or to the splenium and peripheral frontoparietal white matter.