Formyl-methanofuran synthesis in Methanobacterium thermoautotrophicum

The initial step of methanogenesis from CO2 is the formation of formyl-methanofuran (formyl-MFR) from methanofuran (MFR), CO2 and H2. The enzymology of this novel type of CO2 fixation reaction has been difficult to study because formyl-MFR synthesis is subject to a complex activation. Recently, howe...

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Bibliographic Details
Published inFEMS microbiology reviews Vol. 7; no. 3-4; p. 323
Main Authors Bobik, T A, DiMarco, A A, Wolfe, R S
Format Journal Article Conference Proceeding
LanguageEnglish
Published England 1990
Subjects
Aldehyde Oxidoreductases - metabolism
Carbon Dioxide - metabolism
Electron Transport
Euryarchaeota - enzymology
Euryarchaeota - metabolism
Furans - metabolism
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ISSN0168-6445
DOI10.1016/0378-1097(90)90473-4

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Summary:The initial step of methanogenesis from CO2 is the formation of formyl-methanofuran (formyl-MFR) from methanofuran (MFR), CO2 and H2. The enzymology of this novel type of CO2 fixation reaction has been difficult to study because formyl-MFR synthesis is subject to a complex activation. Recently, however, a number of advances have made questions regarding formyl-MFR synthesis more approachable.
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ISSN:0168-6445
DOI:10.1016/0378-1097(90)90473-4