Evaluation of Antiulcer Activity of Ocimum Sanctum in Rats

Aqueous extract of Ocimum sanctum was evaluated for its Antiulcer activity against methanol induced ulcer in Wistar rats. The aqueous extract ofOcimum sanctum at the dose rate of 100mg /kg an 200 mg/kg per orally exhibited significant protection against ethanol induced gastric ulceration. The presen...

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Bibliographic Details
Published inVeterinary World Vol. 2; no. 12 p.465-466; pp. 465 - 466
Main Authors Ghangale, G R, Mahale, Tushar, Jadhav, N D
Format Journal Article
LanguageEnglish
Published Veterinary World 01.12.2009
Subjects
alternative medicine
animal models
anti-ulcer activity
Antioxidant
antioxidant activity
antioxidants
Antiulcer activity
aqueous solutions
dosage
dose response
drug evaluation
gastric mucosa
gastrointestinal agents
Herbal drug
herbal medicines
medicinal plants
methanol
Ocimum tenuiflorum
oral administration
pathogenesis
rats
stomach ulcers
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ISSN0972-8988
2231-0916

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Summary:Aqueous extract of Ocimum sanctum was evaluated for its Antiulcer activity against methanol induced ulcer in Wistar rats. The aqueous extract ofOcimum sanctum at the dose rate of 100mg /kg an 200 mg/kg per orally exhibited significant protection against ethanol induced gastric ulceration. The present investigation revealed that Ocimum sanctum exhibited significant antiulcer activity by enhancing antioxidant potential of gastric mucosa thereby reducing mucosal damage. [Vet World 2009; 2(12.000): 465-466]
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ISSN:0972-8988
2231-0916