Clinical Characteristics and Risk Factors Analysis for Visceral Pleural Invasion in 
Mixed Ground-glass Nodular Lung Adenocarcinoma

Lung cancer is still the malignant tumor with the highest morbidity and mortality in China. Lung adenocarcinoma is the most common subtype, and the number of lung cancer presenting as mixed ground glass nodule (mGGN) in imaging is gradually increasing. Visceral pleural invasion (VPI) is an important...

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Published inZhongguo fei ai za zhi Vol. 25; no. 4; pp. 236 - 244
Main Authors Fu, Chenghao, Jiang, Yiheng, Ge, Jiayun, Yuan, Mei, Wang, Jun
Format Journal Article
LanguageChinese
Published China Chinese Anti-Cancer Association Chinese Antituberculosis Association 20.04.2022
Chinese Anti-Cancer Association; Chinese Antituberculosis Association
Subjects
Adenocarcinoma of Lung - pathology
Antigens
computed tomography
Female
Growth factors
Humans
Lung cancer
lung neoplasms
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - surgery
Male
Medical prognosis
mixed ground glass nodule
Multivariate analysis
Neoplasm Invasiveness
Pleura - pathology
pleural invasion
Retrospective Studies
Risk Factors
Thoracic surgery
Tomography
China
Pleural invasion
Computed tomography
Mixed ground glass nodule
Lung neoplasms
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ISSN1009-3419
1999-6187
1999-6187
DOI10.3779/j.issn.1009-3419.2022.102.07

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Summary:Lung cancer is still the malignant tumor with the highest morbidity and mortality in China. Lung adenocarcinoma is the most common subtype, and the number of lung cancer presenting as mixed ground glass nodule (mGGN) in imaging is gradually increasing. Visceral pleural invasion (VPI) is an important factor affecting the prognosis of mGGN type lung adenocarcinoma. The aim of the study is to explore and analyze the risk factors for VPI in mGGN type lung adenocarcinoma. From November 2016 to November 2019, 128 patients with mGGN lung adenocarcinoma underwent radical surgical resection in the First Affiliated Hospital of Nanjing Medical University. Their clinical data, including imaging, pathological and biological features, were collected and analyzed retrospectively. There were 40 males and 88 females, aged 60.3±9.3 years ranging from 30 to 81 years. Single factor Chi-square test and multivariate Logistic regression were used to analyze the risk factors of VPI in mGGN type lung adenocarcinoma. Among 128 mGGN pa
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ISSN:1009-3419
1999-6187
1999-6187
DOI:10.3779/j.issn.1009-3419.2022.102.07