Early predictive value of serum CRP/ALB and PCT/ALB for the severity of acute pancreatitis

• Published in: Zhongguo lin chuang yan jiu Vol. 37; no. 5; pp. 760 - 763
• Main Author: ZHU Lingjuan, CUI Jing
• Format: Journal Article
• Language: Chinese
• Published: The Editorial Department of Chinese Journal of Clinical Research 01.05.2024
• Subjects: acute pancreatitis; c-reactive protein to albumin ratio; procalcitonin to albumin ratio; severe; severity
• ISSN: 1674-8182
• DOI: 10.13429/j.cnki.cjcr.2024.05.022

Objective To explore the early predictive value of the C-reactive protein to albumin ratio (CRP/ALB) and procalcitonin to albumin ratio (PCT/ALB) for the severity of acute pancreatitis (AP). Methods A retrospective analysis was conducted on the clinical data of 133 patients with AP who were hospitalized at the Second Affiliated Hospital of Zhengzhou University from January 2020 to December 2022.Among them, there were 85 cases in the non-severe acute pancreatitis (NSAP) group and 48 cases in the severe acute pancreatitis (SAP) group. Univariate analysis of variance was performed on the age, total hospital stays, ICU admission rate, amylase, white blood cell (WBC) count, hematocrit (HCT), Ca2+, serum creatinine (Cr), blood urea nitrogen (BUN), D-dimer, serum procalcitonin (PCT), CRP, serum albumin (ALB), PCT/ALB, CRP/ALB in two groups to screen the indicators related to the severity of AP. Subsequently, ROC curve analysis and binary logistic regression analysis were condacted on the selected indicators. Results