燕麦麸β-葡聚糖降血糖及抗氧化作用研究
目的研究燕麦麸β-葡聚糖的降血糖和抗氧化功效。方法将小鼠分为正常组和模型组,模型组通过注射四氧嘧啶建立糖尿病模型。比较分析各组小鼠体重、摄食量、饮水量、血糖值、耐糖量、肝脏超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和丙二醛(MDA)含量。结果高剂量组对糖尿病小鼠摄食饮水量的减少和体重增加有显著影响且高剂量组小鼠血糖值降低25.39%。燕麦麸β-葡聚糖对正常小鼠的体重、饮水量、摄食量、血糖值、耐糖量没有明显的作用。与对照组比较,模型组小鼠血糖曲线下面积、SOD、GSH-PX的活性显著提高,体内MDA的含量显著降低。结论燕麦麸β-葡聚糖能降低糖尿病小鼠的血糖值和提高糖尿病小鼠的抗...
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| Published in | 食品安全质量检测学报 no. 6; pp. 2131 - 2137 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
天津科技大学食品工程与生物技术学院,天津,300457
2015
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| Subjects | |
| Online Access | Get full text |
| ISSN | 2095-0381 |
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| Abstract | 目的研究燕麦麸β-葡聚糖的降血糖和抗氧化功效。方法将小鼠分为正常组和模型组,模型组通过注射四氧嘧啶建立糖尿病模型。比较分析各组小鼠体重、摄食量、饮水量、血糖值、耐糖量、肝脏超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和丙二醛(MDA)含量。结果高剂量组对糖尿病小鼠摄食饮水量的减少和体重增加有显著影响且高剂量组小鼠血糖值降低25.39%。燕麦麸β-葡聚糖对正常小鼠的体重、饮水量、摄食量、血糖值、耐糖量没有明显的作用。与对照组比较,模型组小鼠血糖曲线下面积、SOD、GSH-PX的活性显著提高,体内MDA的含量显著降低。结论燕麦麸β-葡聚糖能降低糖尿病小鼠的血糖值和提高糖尿病小鼠的抗氧化能力,对正常小鼠没有影响。 |
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| AbstractList | 目的研究燕麦麸β-葡聚糖的降血糖和抗氧化功效。方法将小鼠分为正常组和模型组,模型组通过注射四氧嘧啶建立糖尿病模型。比较分析各组小鼠体重、摄食量、饮水量、血糖值、耐糖量、肝脏超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和丙二醛(MDA)含量。结果高剂量组对糖尿病小鼠摄食饮水量的减少和体重增加有显著影响且高剂量组小鼠血糖值降低25.39%。燕麦麸β-葡聚糖对正常小鼠的体重、饮水量、摄食量、血糖值、耐糖量没有明显的作用。与对照组比较,模型组小鼠血糖曲线下面积、SOD、GSH-PX的活性显著提高,体内MDA的含量显著降低。结论燕麦麸β-葡聚糖能降低糖尿病小鼠的血糖值和提高糖尿病小鼠的抗氧化能力,对正常小鼠没有影响。 目的：研究燕麦麸β-葡聚糖的降血糖和抗氧化功效。方法将小鼠分为正常组和模型组，模型组通过注射四氧嘧啶建立糖尿病模型。比较分析各组小鼠体重、摄食量、饮水量、血糖值、耐糖量、肝脏超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和丙二醛(MDA)含量。结果高剂量组对糖尿病小鼠摄食饮水量的减少和体重增加有显著影响且高剂量组小鼠血糖值降低25.39%。燕麦麸β-葡聚糖对正常小鼠的体重、饮水量、摄食量、血糖值、耐糖量没有明显的作用。与对照组比较，模型组小鼠血糖曲线下面积、SOD、GSH-PX的活性显著提高，体内MDA的含量显著降低。结论燕麦麸β-葡聚糖能降低糖尿病小鼠的血糖值和提高糖尿病小鼠的抗氧化能力，对正常小鼠没有影响。 |
| Abstract_FL | Objective To study the effects of oat bran β-glucan on hyooglycemic and antioxidant. Methods The mice were divided into normal group and model group. The models of experimental diabetes were built by injecting Alloxan in mouse. The body weight, food intake, water intake, blood glucose levels, the glucose tolerance, superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and malondialdehyde (MDA) in the liver, and organ index of mice were analyzed. Results The high dosage group could reduce the average amount ingestion and water intake and increase the average weight of diabetic mice obviously, and the glucose levels of high dosage group were 25.39%. Oat bran β-glucan made no significant effect on normal mice’s weight, water intake, food intake, blood glucose level, and glucose tolerance. Compared with control group, model group in mice the area under blood glucose curve, SOD, and GSH-PX activity were increased significantly, and the body MDA content was decreased significantly. Conclusion The results indicate that oat bran β-glucan has no effect on normal mice but can decrease the blood glucose levels of diabetic mice and improve the antioxidant capacity of diabetic mice. |
| Author | 赵范 刘会平 刘晓庆 张晨萍 王宇 徐娇娇 |
| AuthorAffiliation | 天津科技大学食品工程与生物技术学院 |
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| Author_FL | ZHAO Fan LIU Xiao-Qing LIU Hui-Ping WANG Yu ZHANG Chen-Ping XU Jiao-Jiao |
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| Keywords | β-glucan antioxidant oats bran 降血糖 燕麦麸 抗氧化 hypoglycemic effect β-葡聚糖 |
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| Notes | ZHAO Fan;LIU Hui-Ping;LIU Xiao-Qing;ZHANG Chen-Ping;WANG Yu;XU Jiao-Jiao;College of Food Engineering and Biotechnology,Tianjin University of Science and Technology 11-5956/TS |
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| SubjectTerms | β-葡聚糖 抗氧化 燕麦麸 降血糖 |
| Title | 燕麦麸β-葡聚糖降血糖及抗氧化作用研究 |
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