Enrolling Adolescents in Research on HIV and Other Sensitive Issues: Lessons from South Africa
Jerome Singh and colleagues present the ethical and legal challenges surrounding the enrollment of adolescents in HIV observational studies and other types of sensitive research.
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| Published in | PLoS medicine Vol. 3; no. 7; p. e180 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Public Library of Science
01.07.2006
Public Library of Science (PLoS) |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1549-1676 1549-1277 1549-1676 |
| DOI | 10.1371/journal.pmed.0030180 |
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| Abstract | Jerome Singh and colleagues present the ethical and legal challenges surrounding the enrollment of adolescents in HIV observational studies and other types of sensitive research. |
|---|---|
| AbstractList | Jerome Singh and colleagues present the ethical and legal challenges surrounding the enrollment of adolescents in HIV observational studies and other types of sensitive research. |
| Audience | Academic |
| Author | Williamson, Carolyn Abdool Karim, Quarraisha Abdool Karim, Salim S Mlisana, Koleka Gray, Clive Gray, Andrew Singh, Jerome Amir Govender, Michelle |
| Author_xml | – sequence: 1 givenname: Jerome Amir surname: Singh fullname: Singh, Jerome Amir – sequence: 2 givenname: Salim S surname: Abdool Karim fullname: Abdool Karim, Salim S – sequence: 3 givenname: Quarraisha surname: Abdool Karim fullname: Abdool Karim, Quarraisha – sequence: 4 givenname: Koleka surname: Mlisana fullname: Mlisana, Koleka – sequence: 5 givenname: Carolyn surname: Williamson fullname: Williamson, Carolyn – sequence: 6 givenname: Clive surname: Gray fullname: Gray, Clive – sequence: 7 givenname: Michelle surname: Govender fullname: Govender, Michelle – sequence: 8 givenname: Andrew surname: Gray fullname: Gray, Andrew |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/16608384$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/j.1467-8519.2004.00395.x 10.1016/S1054-139X(01)00291-9 10.2105/AJPH.94.6.918 10.1056/NEJM200003303421303 10.1136/sti.75.3.139 |
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| Copyright | COPYRIGHT 2006 Public Library of Science 2006 Singh et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Singh JA, Abdool Karim SS, Abdool Karim Q, Mlisana K, Williamson C, et al. (2006) Enrolling Adolescents in Research on HIV and Other Sensitive Issues: Lessons from South Africa. PLoS Med 3(7): e180. doi:10.1371/journal.pmed.0030180 Copyright: © 2006 Singh et al. 2006 |
| Copyright_xml | – notice: COPYRIGHT 2006 Public Library of Science – notice: 2006 Singh et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Singh JA, Abdool Karim SS, Abdool Karim Q, Mlisana K, Williamson C, et al. (2006) Enrolling Adolescents in Research on HIV and Other Sensitive Issues: Lessons from South Africa. PLoS Med 3(7): e180. doi:10.1371/journal.pmed.0030180 – notice: Copyright: © 2006 Singh et al. 2006 |
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| Keywords | HIV Infections Guidelines as Topic Confidentiality Ethics Committees, Research Humans Adolescent South Africa Clinical Trials as Topic Personal Autonomy Research Subjects Ethics, Research |
| Language | English |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 All authors are at the Centre for AIDS Programme of Research in South Africa, Congella, South Africa, and at the Nelson R. Mandela School of Medicine, University of KwaZulu–Natal, Durban, South Africa. Jerome Amir Singh is in the Department of Public Health Sciences and in the Joint Centre for Bioethics, University of Toronto, Ontario, Canada, and at the Howard College School of Law, University of KwaZulu–Natal, Durban, South Africa. Salim S. Abdool Karim and Quarraisha Abdool Karim are in the Division of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America. Salim S. Abdool Karim is also at the Weiss School of Medicine, Cornell University, New York, New York, United States of America. Carolyn Williamson is in the Department of Virology, University of Cape Town. Rondebosch, South Africa. Clive Gray is at the National Institute of Communicable Diseases, Johannesburg, South Africa. Michelle Govender is part of the AIDS Law Project, Johannesburg, South Africa. Competing Interests: The authors have declared that no competing interests exist. |
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| References | Quinn (JOURNAL-PMED-0030180-B2) 2000; 342 Wilson (JOURNAL-PMED-0030180-B3) 2001; 29 Macpherson (JOURNAL-PMED-0030180-B22) 2004; 18 Abdool Karim (JOURNAL-PMED-0030180-B1) 1999; 75 Quinn (JOURNAL-PMED-0030180-B23) 2004; 94 Strode (JOURNAL-PMED-0030180-B17) 2005; 95 Slack (JOURNAL-PMED-0030180-B6) 2005; 95 Strode (JOURNAL-PMED-0030180-B7) 2005; 95 Strode (JOURNAL-PMED-0030180-B5) 2005; 101 Slack (JOURNAL-PMED-0030180-B14) 2005; 95 10738050 - N Engl J Med. 2000 Mar 30;342(13):921-9 15341040 - Bioethics. 2004 Jun;18(3):283-92 15249289 - Am J Public Health. 2004 Jun;94(6):918-22 15889851 - S Afr Med J. 2005 Apr;95(4):265-8 16327927 - S Afr Med J. 2005 Sep;95(9):682-4 10448384 - Sex Transm Infect. 1999 Jun;75(3):139-40 16201004 - S Afr Med J. 2005 Aug;95(8):598-601 15889852 - S Afr Med J. 2005 Apr;95(4):269-71 11530299 - J Adolesc Health. 2001 Sep;29(3 Suppl):8-18 |
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| SubjectTerms | Acquired immune deficiency syndrome Adolescent Adolescents AIDS Bioethics Clinical Trials as Topic Confidentiality Epidemiology/Public Health Ethics Ethics Committees, Research Ethics, Research Guidelines as Topic Health aspects Health Policy HIV HIV (Viruses) HIV Infection/AIDS HIV Infections HIV/AIDS Human immunodeficiency virus Humans Infectious Diseases Medical Law Medicine in Developing Countries Pediatrics Personal Autonomy Policy Forum Research Methods Research Subjects Sexual Health South Africa Teenagers Vaccines Youth |
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| Title | Enrolling Adolescents in Research on HIV and Other Sensitive Issues: Lessons from South Africa |
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