Clinical Features and Neuroimaging Findings in Patients with Cerebral Fat Embolism

INTRODUCTION Cerebral fat embolism (CFE) is a rare but potentially lethal disease that is usually complicated by long bone fracture, which can develop over 12-72 h. Since the main fbrm of treatment for CFE is supportive, early diagnosis, prevention, and appropriate treatment can reduce mortality and...

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Published inChinese medical journal Vol. 129; no. 7; pp. 874 - 876
Main Authors Han, Yang-Tong, Tang, Jing, Gao, Zhi-Qiang, Hu, Hong-Tao
Format Journal Article
LanguageEnglish
Published China Wolters Kluwer - Medknow Publications 05.04.2016
Medknow Publications and Media Pvt. Ltd
Lippincott Williams & Wilkins Ovid Technologies
Department of Neurology, Beijing Jishuitan Hospital, Beijing 100035, China%Department of Orthopedic Osteology, Beijing Jishuitan Hospital, Beijing 100035, China%Department of Trauma Osteology, Beijing Jishuitan Hospital, Beijing 100035, China
Medknow Publications & Media Pvt Ltd
Wolters Kluwer
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ISSN0366-6999
2542-5641
2542-5641
DOI10.4103/0366-6999.178963

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Summary:INTRODUCTION Cerebral fat embolism (CFE) is a rare but potentially lethal disease that is usually complicated by long bone fracture, which can develop over 12-72 h. Since the main fbrm of treatment for CFE is supportive, early diagnosis, prevention, and appropriate treatment can reduce mortality and the development of complications. However, due to symptom heterogeneity and imprecise diagnostic methods, CFE may be masked by other clinical conditions that make early detection challenging. Given its low incidence, most clinical studies of CFE are single cases or small case series. To characterize the features of CFE, clinical manifestations, laboratory examinations, and neuroimaging data were evaluated in a large sample of patients with CFE.
Bibliography:INTRODUCTION Cerebral fat embolism (CFE) is a rare but potentially lethal disease that is usually complicated by long bone fracture, which can develop over 12-72 h. Since the main fbrm of treatment for CFE is supportive, early diagnosis, prevention, and appropriate treatment can reduce mortality and the development of complications. However, due to symptom heterogeneity and imprecise diagnostic methods, CFE may be masked by other clinical conditions that make early detection challenging. Given its low incidence, most clinical studies of CFE are single cases or small case series. To characterize the features of CFE, clinical manifestations, laboratory examinations, and neuroimaging data were evaluated in a large sample of patients with CFE.
11-2154/R
Cerebral Fat Enlbolism; Clinical Features; Neuroimaging Findings
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ISSN:0366-6999
2542-5641
2542-5641
DOI:10.4103/0366-6999.178963