Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study

• Published in: Indian journal of ophthalmology Vol. 70; no. 4; pp. 1302 - 1306
• Main Authors: Kohli, Gaurav Mohan, Shenoy, Pratik, Halim, Danish, Nigam, Saurabh, Shetty, Sachin, Talwar, Dinesh, Sen, Alok
• Format: Journal Article
• Language: English
• Published: India Medknow Publications & Media Pvt Ltd 01.04.2022; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Edition: 2
• Subjects: Adult; Aged; choroidal detachment; Choroidal Effusions; Drug therapy; Eye; Humans; Injection; Methods; Middle Aged; needle; Pilot Projects; Preoperative care; Prospective Studies; Retina; Retinal detachment; Retinal Detachment - complications; Retinal Detachment - diagnosis; Retinal Detachment - surgery; Retrospective Studies; Special Focus, Retina, Original; Special Focus, Retina, Original Article; suprachoroidal; Surgery; Triamcinolone; Triamcinolone Acetonide; Vitrectomy - methods; India; suprachoroidal; triamcinolone acetonide; Choroidal detachment; needle; retinal detachment
• ISSN: 0301-4738; 1998-3689; 1998-3689
• DOI: 10.4103/ijo.IJO_1788_21

Purpose: To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD). Methods: This was a prospective, noncomparative, interventional pilot study. All consecutive patients presenting with RD and coexisting CD underwent transconjunctival injection of SCTA before proceeding with vitrectomy/scleral buckle surgery. Sequential ultrasound B scans were performed for assessing the change in height of the CD. Results: The mean age of the cohort was 53.8 ± 10.8 years (range: 39-72 years). The CD was present in a median of 3 quadrants; the cumulative mean CD height was 5.59 mm (range: 2.02-9.42 mm). Following SCTA, a successful response (>50% reduction) was seen in five eyes by day 3 and in two eyes by day 5. Three eyes failed to respond to SCTA and required surgical drainage before proceeding with vitrectomy. No intraprocedural injection-related complications were noted. A transient rise in the intraocular pressure (30 mmHg) was seen in one eye following vitrectomy and was managed successfully with topical antiglaucoma medications Conclusion: Suprachoroidal administration of triamcinolone appears to be a safe and effective technique to achieve CD resolution in eyes with RRD.