Genotypic Heterogeneity of Orientia tsutsugamushi in Scrub Typhus Patients and Thrombocytopenia Syndrome Co-infection, Myanmar

• Published in: Emerging infectious diseases Vol. 26; no. 8; pp. 1878 - 1881
• Main Authors: Win, Aye Marlar, Nguyen, Yen Thi Hai, Kim, Yuri, Ha, Na-Young, Kang, Jun-Gu, Kim, Hongil, San, Bo, Kyaw, Okkar, Htike, Wah Win, Choi, Dong-Ok, Lee, Keun-Hwa, Cho, Nam-Hyuk
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.08.2020; Centers for Disease Control and Prevention
• Subjects: Age; Antigens; Bacteria; coinfection; differential diagnosis genotypes; Dispatch; Epidemiology; Fever; Genotypic Heterogeneity of; Health aspects; Illnesses; in Scrub Typhus Patients and Thrombocytopenia Syndrome Co-infection, Myanmar; Infection; Infections; Infectious diseases; Medical diagnosis; Medical research; mite-borne infections; Myanmar; Orientia tsutsugamushi; Pathogens; Phylogenetics; Resveratrol; Scrub typhus; Thrombocytopenia; Typhus; Vietnam; South Korea; Myanmar (Burma); Thailand; Asia; China; Myanmar; viruses; thrombocytopenia syndrome virus; vector-borne infections; co-infection; Bacteria; mite-borne infections; Orientia tsutsugamushi; phylogenic analysis; tsutsugamushi; differential diagnosis genotypes; scrub typhus
• ISSN: 1080-6040; 1080-6059; 1080-6059
• DOI: 10.3201/eid2608.200135

Serologic and molecular surveillance of serum collected from 152 suspected scrub typhus patients in Myanmar revealed Orientia tsutsugamushi of genotypic heterogeneity. In addition, potential co-infection with severe fever with thrombocytopenia syndrome virus was observed in 5 (3.3%) patients. Both scrub typhus and severe fever with thrombocytopenia syndrome are endemic in Myanmar.