Processed and Unprocessed Red Meat Consumption and Incident Type 2 Diabetes Among French Women

• Published in: Diabetes care Vol. 35; no. 1; pp. 128 - 130
• Main Authors: Lajous, Martin, Tondeur, Laura, Fagherazzi, Guy, de Lauzon-Guillain, Blandine, Boutron-Ruaualt, Marie-Christine, Clavel-Chapelon, Françoise
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.01.2012
• Subjects: adverse effects; alcohols; Biological and medical sciences; body mass index; carbohydrates; Cohort Studies; Diabetes; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 2 - epidemiology; Diabetes therapy; Diabetes. Impaired glucose tolerance; Diet; education; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; epidemiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Feeding Behavior; Female; France; France - epidemiology; fruits; Health risk assessment; Hormone replacement therapy; Humans; hypercholesterolemia; hypertension; Incidence; Life Sciences; Meat; meat consumption; Meat Products; Meat Products - adverse effects; Medical sciences; menopause; Metabolic diseases; Middle Aged; Miscellaneous; multivariate analysis; noninsulin-dependent diabetes mellitus; Nutrition research; omega-3 fatty acids; Original Research; physical activity; Prospective Studies; Public health; Public health. Hygiene; Public health. Hygiene-occupational medicine; Questionnaires; red meat; Risk factors; Santé publique et épidémiologie; Surveys and Questionnaires; Type 2 diabetes; Validation studies; vegetables; Women; Womens health; France; Europe; Endocrinopathy; Consumption; Type 2 diabetes; Human; French; Nutrition; Female; Metabolic diseases; Red meat; Woman; Endocrinology; Food
• ISSN: 0149-5992; 1935-5548; 1935-5548; 0149-5992
• DOI: 10.2337/dc11-1518

To evaluate the relation of processed and unprocessed red meat and incident type 2 diabetes. We conducted a prospective study among 66,118 disease-free French women with dietary information from a validated questionnaire. Between 1993 and 2007, we identified 1,369 cases of incident diabetes. Multivariate analyses were adjusted for age, education, region, smoking, BMI, hypertension, hypercholesterolemia, physical activity, parental history of diabetes, menopause, hormone replacement therapy, alcohol, calories, n-3 fatty acids, carbohydrates, coffee, fiber, and fruits and vegetables. Comparing the highest category of processed meat intake, ≥5 servings/week (median, 48 g/day), to the lowest, <1 serving/week (median, 5 g/day), processed meat was significantly associated with incident diabetes (hazard ratio 1.30 [95% CI 1.07-1.59], P trend = 0.0007; for 1 serving/day, 1.29 [1.14-1.45]). Unprocessed red meat was not associated with diabetes. In this large prospective cohort of French women, a direct association was observed only for processed red meat and type 2 diabetes.