1125-P: Real-World Pediatric Outcomes of Hybrid Closed-Loop Systems at a Large Urban Center

• Published in: Diabetes (New York, N.Y.) Vol. 72; no. Supplement_1; p. 1
• Main Authors: TILLOTSON, CARA V., NICHOLS, PRESLEY H., MOFFORD, KAISHA, LEIBEL, NATASHA, GANDICA, RACHELLE
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 20.06.2023
• Subjects: Data collection; Hypoglycemia; Pediatrics; Quality of life; Surveys
• ISSN: 0012-1797; 1939-327X
• DOI: 10.2337/db23-1125-P

Objectives: To study the real-world effect of hybrid closed loop systems (HCLS) on glycemic control and quality of life (QoL) in pediatric patients with T1D. Methods: Patients 2-20 years old with T1D for ≥ 1 year were recruited when starting t:slim x2 with CIQ (TS) or Omnipod 5 (O5). We collected time in range (TIR), time low (BG <70 mg/dl), A1c, and QoL survey responses at baseline and 3 months. Kruskal-Wallis rank sum test and chi-squared test were used for data analysis. Results: Baseline data is in Figure 1. TIR improved by 7% after 3 months of HCLS use (p=0.004). Time low was unchanged after 3 months (p=0.3). Figure 2 shows results by subject. Discussion: In this real-world study, HCLS improved TIR at 3 months without change in hypoglycemia. Data collection, enrollment, and analysis are ongoing with more results (A1c, QoL surveys) expected shortly.