临床药师参与1例心脏瓣膜置换术后合并肝功能异常患者华法林个体化抗凝治疗

目的：探讨临床药师在华法林个体化抗凝治疗中的作用。方法：回顾分析临床药师参与1例心脏瓣膜置换术后合并肝功能异常患者华法林抗凝治疗的全过程。结果：临床药师从患者基因型、肝功能及药物相互作用角度分析华法林抗凝过量原因,对患者实施华法林个体化抗凝治疗,并对其进行药学监护。结论：临床药师参与患者的个体化抗凝治疗,可提高抗凝治疗成功率,降低患者抗凝风险。...

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Bibliographic Details
Published in中国医院用药评价与分析 no. 7; pp. 987 - 989
Main Author 张丽 刘俊
Format Journal Article
LanguageChinese
Published 芜湖市第一人民医院药剂科,安徽芜湖,241001%皖南医学院弋矶山医院药剂科,安徽芜湖,241001 2015
Subjects
临床药师
华法林
抗凝治疗
肝功能异常
药学监护
临床药师
Liver dysfunction
Clinic pharmacist
肝功能异常
Warfarin
抗凝治疗
华法林
Anticoagulation treatment
Pharmaceutical care
药学监护
Online AccessGet full text
ISSN1672-2124
DOI10.14009/j.issn.1672-2124.2015.07.057

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Summary:目的：探讨临床药师在华法林个体化抗凝治疗中的作用。方法：回顾分析临床药师参与1例心脏瓣膜置换术后合并肝功能异常患者华法林抗凝治疗的全过程。结果：临床药师从患者基因型、肝功能及药物相互作用角度分析华法林抗凝过量原因,对患者实施华法林个体化抗凝治疗,并对其进行药学监护。结论：临床药师参与患者的个体化抗凝治疗,可提高抗凝治疗成功率,降低患者抗凝风险。
Bibliography:Liver dysfunction; Warfarin; Anticoagulation treatment; Clinic pharmacist; Pharmaceutical care
OBJECTIVE： To explore the role of clinic pharmacist in warfarin individualized anticoagulant treatment.METHODS： Clinical pharmacist＇s experience with treatment of one patient with warfarin individualized anticoagulant treatment was analyzed retrospectively. RESULTS： Clinical pharmacists implemented individualized anticoagulatant treatment based on patient＇s genotype,liver function and drug interaction,analyzed the reasons for anticoagulant overdose and provided pharmaceutical care for the patient. CONCLUSIONS： Clinical pharmacist involved in warfarin individualized anticoagulant treatment can improve the success rate and reduce the risk of anticoagulant therapy.
ZHANG Li,LIU Jun（1. Dept. of Pharmacy, Wuhu First People＇s Hospital, Anhui Wuhu 241001, China;2. Dept. of Pharmacy, Yijishan Hospital of Wannan Medical College ,Anhui Wuhu 241001 ,China）
11-4975/R
ISSN:1672-2124
DOI:10.14009/j.issn.1672-2124.2015.07.057