Quercetin with the potential effect on allergic diseases
Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releas...
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Published in | Allergy, asthma, and clinical immunology Vol. 16; no. 1; pp. 36 - 11 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
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London
BioMed Central
14.05.2020
BioMed Central Ltd BMC |
Subjects | |
Online Access | Get full text |
ISSN | 1710-1492 1710-1484 1710-1492 |
DOI | 10.1186/s13223-020-00434-0 |
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Abstract | Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD). |
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AbstractList | Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD). Abstract Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD). Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD).Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD). |
ArticleNumber | 36 |
Audience | Academic |
Author | Ganjalikhani Hakemi, Mazdak kasiri, Neda Sadat Hosseini, Mahnaz Jafarinia, Morteza Fathi, Farshid Eskandari, Nahid Fazel, Niloofar |
Author_xml | – sequence: 1 givenname: Morteza surname: Jafarinia fullname: Jafarinia, Morteza organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences – sequence: 2 givenname: Mahnaz surname: Sadat Hosseini fullname: Sadat Hosseini, Mahnaz organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences – sequence: 3 givenname: Neda surname: kasiri fullname: kasiri, Neda organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences – sequence: 4 givenname: Niloofar surname: Fazel fullname: Fazel, Niloofar organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences – sequence: 5 givenname: Farshid surname: Fathi fullname: Fathi, Farshid organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences – sequence: 6 givenname: Mazdak surname: Ganjalikhani Hakemi fullname: Ganjalikhani Hakemi, Mazdak organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences – sequence: 7 givenname: Nahid surname: Eskandari fullname: Eskandari, Nahid email: neskandari@med.mui.ac.ir organization: Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Applied Physiology Research Center, Isfahan Cardiovascular Research Institute, Department of Physiology, School of Medicine, Isfahan University of Medical Sciences |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32467711$$D View this record in MEDLINE/PubMed |
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Keywords | Allergy Quercetin Asthma |
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PublicationTitle | Allergy, asthma, and clinical immunology |
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Snippet | Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine... Abstract Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting... |
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SubjectTerms | Airway management Allergies Allergology Allergy Asthma Atopic dermatitis B cells Bioflavonoids Cytokines Eczema Flavones Flavonoids Gene expression Genotype & phenotype Histamine Immunoglobulin E Immunology Immunomodulators Inflammation Kinases Lymphocytes Medical care, Cost of Medical research Medicine Medicine & Public Health Medicine, Experimental Metabolites Neutrophils Permeability Pneumology/Respiratory System Pollutants Polyphenols Proteins Quercetin Review Signal transduction Tumor necrosis factor-TNF |
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Title | Quercetin with the potential effect on allergic diseases |
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