Phylogenetic Analysis of Astrovirus and Kobuvirus in Korean Dogs

• Published in: Journal of Veterinary Medical Science Vol. 76; no. 8; pp. 1141 - 1145
• Main Authors: LIM, Seong-In, CHO, Yoon-Young, KIM, Yong Kwan, CHOI, Sarah, AN, Dong-Jun, SONG, Jae-Young
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2014; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Animals; Astroviridae - genetics; Astroviridae Infections - veterinary; Astroviridae Infections - virology; Astrovirus; Base Sequence; canine astrovirus; canine kobuvirus; Cluster Analysis; Diarrhea - veterinary; Diarrhea - virology; DNA Primers - genetics; Dog Diseases - virology; Dogs; Feces - virology; Kobuvirus - genetics; Molecular Sequence Data; Phylogeny; Picornaviridae Infections - veterinary; Picornaviridae Infections - virology; Republic of Korea; Sequence Analysis, DNA - veterinary; South Korea; Virology; Republic of Korea
• ISSN: 0916-7250; 1347-7439; 1347-7439
• DOI: 10.1292/jvms.13-0585

Astroviruses and kobuviruses are frequently found in mammalian feces, including that of humans. The present study examined fecal samples from 91 Korean dogs suffering from diarrhea. Canine astroviruses (CAstVs) and canine kobuviruses (CKoVs) were identified in 2 (2.1%) and 46 (50.6%) dogs, respectively. Nucleotide sequence analysis coupled with phylogenetic analysis using the neighbor-joining method showed that CAstVs clustered into four genetically diverse groups. Two Korean CAstVs belonged to group 2 alongside strains isolated in Italy and France. Twelve of the Korean CKoVs belonged to a single clade, along with strain UK003 identified in the UK and six CKoVs identified in the USA. Thus, the results suggest that the Korean strain of CAstV is closely related to strains isolated in Europe. Surely, CKoV in South Korea could identify the circulation among dogs population.